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Orange urine in the morning. Chronic HBV and pregnant
Has anyone that has chronic HBV have orange urine in the morning? After drinking more water urine is yellow again but seems to happen every morning lately. Is this a sign of flare, inflammation, or more?
I have high VL 4 million, ALT 384, AST 233 Please help.
I have high VL 4 million, ALT 384, AST 233 Please help.
Hi Cabin3, tenofovir was approved by the fda back in 2008, meaning the longest time it has been in use by chronic hbvers is eight years. Tenofovir doesn't have resistance issues, and not adverse sides either, except for those who have kidney disease in which case it may exacerbate the disease. Also tenofovir has proven to be effective against hbv on long term use.
For those with kidney problems there are equally effective drugs such as entecavir, whereas the tenofovir prodrug taf, which is kidney friendly, but equally effective as tdf, is almost ready for hbv patients. According to the study that i'm linking here "stopoing tenofovir is safe for people with hepb on long term therapy".
Regarding scarring or degree of fibrosis, i think it is difficult to tell before a fibroscan and/or biopsy is done. I have been diagnosed with chronic hbv a bit over a year; my alt have been maximum 40, vl max. 2700iu, normal us, and normal fibroscan. The doctors have, therefore, not decided to start treatment on me, i'm just monitoring. Wish you again best of luck with your pregnancy and eventual hbv therapy.
http://www.infohep.org/Stopping-tenofovir-is-safe-for-people-with-hepatitis-B-on-long-term-therapy/page/2973146/
For those with kidney problems there are equally effective drugs such as entecavir, whereas the tenofovir prodrug taf, which is kidney friendly, but equally effective as tdf, is almost ready for hbv patients. According to the study that i'm linking here "stopoing tenofovir is safe for people with hepb on long term therapy".
Regarding scarring or degree of fibrosis, i think it is difficult to tell before a fibroscan and/or biopsy is done. I have been diagnosed with chronic hbv a bit over a year; my alt have been maximum 40, vl max. 2700iu, normal us, and normal fibroscan. The doctors have, therefore, not decided to start treatment on me, i'm just monitoring. Wish you again best of luck with your pregnancy and eventual hbv therapy.
http://www.infohep.org/Stopping-tenofovir-is-safe-for-people-with-hepatitis-B-on-long-term-therapy/page/2973146/
Hi Cabin3, i think orange coloured urine in the morning is normal for most people, because of absence of water intake during the night. I also have it; in my case it is such strong orange color that i'm sometimes scared whether it is not blood. But as i drink more water during the day, it becomes normal light colored urine.
Regarding your treatment options during your pregnancy, i think it is very important you take the matter seriously with your doctor/hepatologist so that you both take the right decision whether to begin with antivirals or not. Your viral load and lft tests are at a level that warrant treatment. Also remember when you suppress the virus by antivirals, then there will be minimal chance of passing the virus to the newborn. I wish you good luck.
Regarding your treatment options during your pregnancy, i think it is very important you take the matter seriously with your doctor/hepatologist so that you both take the right decision whether to begin with antivirals or not. Your viral load and lft tests are at a level that warrant treatment. Also remember when you suppress the virus by antivirals, then there will be minimal chance of passing the virus to the newborn. I wish you good luck.
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Liver patient: thank you for your response. I'm taking this matter extremely seriously -- I'm the kind of person that doesn't even take pain killers for headache. I'm very scared about this matter of taking drugs for the rest of my life. Do you know the longest timeframe anyone has been on viread? I'm afraid that it could cause other issues. I'm pushing to have an ultrasound and fibroscan during this pregnancy. Is it conceivable that there is no scarring even with elevated VL, ALT and AST? Can I ask how long you have been on treatment? I was pregnant three years ago and my ALT and AST was highly elevated but came down after a few months after delivery : ALT 70, AST 38. What are your thoughts
cabin,please start treatment now,your LFTS are very high,why you are putting yourself in danger,look at me i m pregnant and taking tdf,baby is growing,and one more thing,in my last pregnancy my viral load was o,and my lfts were normal always 22to 35 in my pregnancy,but after delivery my LFTS keep rising almost 3 years,but not more than 68,so your condition is very dangerous,after delivery your ALT and AST keep rising,
1 Comments
Hi Neeli, I'm really considering going on the viread. I've just been so scared of the side effects like lactic acidosis. I'm trying to push for an ultrasound and fibroscan but my Nurse Practitioner says that it may be hard to see the liver bc of how far along the pregnancy is. I will push one more time. I believe you said your doctor plan to have you on for 2 more years, correct? Which would mean that you have been on viread for about 8 years? Thank you and I will keep you posted for I see the NP tomorrow.
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