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BEST TREATMENT OPTION

Guys fibrous scan result shows 7.8kpa result f1 to f2  the hepatologist doctors says mild fibrosis but HBV DNA show 7998IU/ml LFT normal hbeag negetive she wanted to start peg interferon  and she said if we could not achieve undetected by 12weeks of treatment we will switch to tenofovir for life am scared I don't want to take tenofovir for life . Another doctor said I should not treat since HBV DNA IS Not more than 10000 and LFT normal ,  please what is the best treatment option for this situation I want the viral load to reach undetected and remain there for life NOTE  use peginteron in 2010 for 24 weeks reduce viral load from 150million to 28000 and seroconversion from hbeag positive to negetive is it still advisable to use it again 48 weeks now
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you clearly dont live in a free country, too bad
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but is it the same doctor or some new one ?
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@steff2011 I hope it will help again this second time
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my god that s not a doctor, pegintf for hbv is 1-2years and response is hbsag decline
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It was lack of knowledge then my doctor feel I have respond according to him then my liver was perfectly in good condition in 2010 with no sign of damage that is the reason for stop
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Why did you do only 24 weeks before ? Especially when you responded, decreased viral load and HBe seroconverted. Was it doctor's decision ?
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@stef2011 thanks for the quick response I av send my blood for hsag quantitative test the result will out in two weeks . 1) is it safe for me to use pegylated interferon for f1/f2 fibrosis?  2) can my liver regress the fibrosis to normal liver ? Peg interferon help me to reduce my viral load from 150million to 25000 copies/ml and seroconversion from hbeag positive to hbeag negetive in 2010 . Presently my ALT is 10.2 IU/L and AST 7.6 IU/L  3) do I have a high chance to response to interferon and possible cure
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can t you pay a nurse to come home and do what you need, you sound like in a fascist place where you are not allowed to have the services you like that you pay for.....
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I ask my new GI and her nurses about doing this and they said no. I will check their forums for more information.
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you get a nurse to draw and ship by fedex, people with CFS already do this to ship in europe because US has also no tests for so many diseases, more info how they do on their forums
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The Indian lab said they would take samples from United States but how do you go about sending it? How do you get your doctor or lab to send it?
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send samples to test to india and use pegintf, hbsag at 12weeks and 24weeks will tell if you are responding, if not stop peg and go for tdf

we posted the indian lab network which accepts sample for hbsag quant, it should be somewhere on old posts, try search indian lab hbsag quantitative
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Avatar universal
You should find a place where you can do this test so people here may tell you more. But in most of the countries Hbv dna > 2000 is prerogative to treat, especially for people with fibrosis like yours.
Why did you used paginf only for 24 weeks in 2010 ?
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@sorte hbsag quantitive test was not available here in Nigeria as at that time. That is the reason it was not done . So please what do you suggest my fibroscan is f1/f2 now 7.8kpa my doc said is mild fibrosis ,1)is it safe for me to start peg interferon treatment again one doctor said is hard on liver that the drug can damage liver more am 37yrs now
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Avatar universal
@sorte hbsag quantitive test was not available here in Nigeria as at that time. That is the reason it was not done . So please what do you suggest my fibroscan is f1/f2 now 7.8kpa my doc said is mild fibrosis ,1)is it safe for me to start peg interferon treatment again one doctor said is hard on liver that the drug can damage liver more am 37yrs now
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Avatar universal
To be honest we don't know what was the impact of interferon treatment on your hbv, because you don't have HBsAg quantitive before and after.
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thanks
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I was 32 yrs old the first tym and now am 37yrs
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How were you handling interferon first time?
How old are you now and how old were you first time you took it?

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@stef2011  thanks for the advice please I want to ask weather I should use peg interferon again or tenofovir note I have use peg interferon before in 2010 and viral load was reduce from 150million to around 25000 and I was seroconversion from hbeag positive to negetive my histologist doctor said he want me to use peg interferon again since the viral load is around 8000 IU/ml now am concern about the safety of peg interferon and tenofovir please which one will be better for me now
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I also agree with doctor1, better to start treatment now because of your fibroscan results.
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in US you can t do nothing unless you travel out for the tests or ship sample to test
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When is the best time to start peginterferon if you don't know hbsag (being in United States). I took Entecavir for 15 months and just got put on Tenofovir for 6 months. Should I start peginterferon after 6 months of Tenofovir? My new GI won't allow both.
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Avatar universal
first doctor had the correct approch although a fibroscan and hbsag quant is more important than hbvdna only

we will switch to tenofovir for life am scared I don't want to take tenofovir for life

if you prefer to keep the virus all life and risk death for hcc or cirrhosis.......

it is not for life anyway, tdf will lower hbsag, pegintf add on will finish the job and also new drugs are available by few years.it will never be for life anyway
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