Aa
My healing on peginf
I've started interferon 5 weeks ago, I will try to keep updating in this thread and put related questions here.
week 0:
ALT 30
HBV DNA 700 IU (few months earlier 5600 so fluctuating)
HBsAg 13.000 IU
HBe-
Fibroscan 5,8 F1/S0
Bisopy F1/A2
week 2: ALT 90
week 5: ALT 245
My doctor said last ALT is from one side good (cleaning infected cells) but from other side he's worring that it has raised so fast. I have to check it in two weeks. He said if it will raise to 400 he will decrease peginf dose to 135mcg cuz he's worring that fulminant hepatitis may occure.
week 0:
ALT 30
HBV DNA 700 IU (few months earlier 5600 so fluctuating)
HBsAg 13.000 IU
HBe-
Fibroscan 5,8 F1/S0
Bisopy F1/A2
week 2: ALT 90
week 5: ALT 245
My doctor said last ALT is from one side good (cleaning infected cells) but from other side he's worring that it has raised so fast. I have to check it in two weeks. He said if it will raise to 400 he will decrease peginf dose to 135mcg cuz he's worring that fulminant hepatitis may occure.
Of course I'd like to continue because at the moment I almost have no sides and last alt was 140.
Could you list me please what are those prolonged pefinf benefits (hcc risk decrease ? fibrosis decrease ?), so I will have some arguments in discussion with my doctor in case he will want to cut it.
Could you list me please what are those prolonged pefinf benefits (hcc risk decrease ? fibrosis decrease ?), so I will have some arguments in discussion with my doctor in case he will want to cut it.
i also think that if no sides at all it is good to go on for 48weeks, hbvdna undetectable should be enough to keep it according to european guidelines.
Do you have any side-effects?
If you don't have them you could finish the full 48 weeks, as peginf does have prolonged effects in reduction of the severity of hepatitis even if it doesn't clear hbsag. It is the decision you should make in consultation with your doctor(s).
The good news is that your dna is negative.
If you don't have them you could finish the full 48 weeks, as peginf does have prolonged effects in reduction of the severity of hepatitis even if it doesn't clear hbsag. It is the decision you should make in consultation with your doctor(s).
The good news is that your dna is negative.
Unfortunatelly on week 25 almost no change in HBsAg in compare to week 12, 7450 IU -> 7180 IU
Not sure if peginf will be continued in that case, although hbv dna qualitive is still negative since week 12.
Not sure if peginf will be continued in that case, although hbv dna qualitive is still negative since week 12.
pth/vitd25oh is definitely very strange during peg, if everything was fine with receptors your pth should be lowest normal while despite vitd25oh over 100ng/ml pth is still mid normal range and not low
so in the end your tissues are still vit d deficient despite all of that vit d, i d go to 10.000-15.000iu daily according to what we see as hbsag result
so in the end your tissues are still vit d deficient despite all of that vit d, i d go to 10.000-15.000iu daily according to what we see as hbsag result
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