Story so far

[aberdeen577]

Hello Everyone,
Right now my stats are :
E antigen negarive
S antigen positive
qHBsAg 16.40 IU/ML
anti HBs <10.00 IU/ML
ALT 29
AST 24
GGT 21
ALP 37
Calcium 2.27 mmol/L
adjusted calcium 2.27 mmol/L

I am currently taking
TDF 1x245mg tablet/day (since September 2011)
Simvastatin 1x20mg tablet per day
Vitamin D3 1x5000IU tablet per day
Blueberry extract 3x60mg tablets per day
Selenium tablet (1) per day

I met with my consultant today and I am so depressed now and disappointed. He will not put me on peginf.because:
-my age
-I have severe fibrosis saying inf can cause liver damage and decompensation
-caucasion
-he has no clinical evidence that it will work with someone so low as 16IU. Says surface antigen needs to be around 500IU/ML for it to work
-it is dangerous to take
-my ALT and AST are too normal; would prefer them elevated
I feel very low now and cannot understand why he cant at least try it for a few months at least.

My question to my learned friends is what can I do now?  I would like to self medicate other oral drugs as a first line to seroconversion before inf. Stef, can you suggest a drug regime that I could look at taking? Inf looks to be a little way off for me right now. I am in N Ireland and I do not have any choice of where to go next.
Thank you.

[stef2011]

i would also double check for tumors and other possible chronic infections, just to stay on the very safe side since nagalase 1.8 is quite high and also common to cancers

my last nagalase test in august 2013 was 1.3nmol/min/mg (down from 6.7 aprl 2011)

[stef2011]

as i thought nagalase is still detectable probably produced by cccdna in infected cells, this may also be the reason some are still exposed to liver cancer after hbv clearance.the remaining cccdna probably keeps producing nagalase which keeps macrophages inactivated

anyway if we see you develop hbsab with nagalase normal, which is less than 0.6, we have a point to support this guess

they have just developed a suppository formulation for goleic gcmaf to reach the liver or you may also try the nebuliser, i think the drops are too weak to lower nagalase
another option is hbv vaccine

[aberdeen577]

Dear Friends,
I had my bloods done just a few weeks back and here are the results..
FIBROSCAN    E   (kPa) 11.70 8.70 -- -- 6.50 -- --
HBsAg  (IU/ml) (cccDNA)-- 12.80 16.40 -- 3.10 -- 0.47-- UND
HBsAb  (mIU/ml) -- <10 <10 -- <10 <10 <10
HBV DNA -- UND --UND--UND -- --
Alpha-feto Protein (0 - 6 KIU/L) -- -- -- 1.50 -- -- --
NAGALASE (0.32-0.95U) -- -- -- 2.20 -- 1.80 --
My surface antigen is not detected now but my antibody is still not registering. I continue to take 10,000 D3 per day with a current reading of 83.3ng/l for vitD.I also take 4 drops sublingually of goleic gcmaf two times per week. I hope now to see my antibodies begin to rise and hopefully I will finally win the fight.

[Jeff912000]

Do what you can.  Yes. stress also causes high BP but it still should not be so high.

Do what you can.  

I meant to say all these things lower BP in an additive fashion not addictive.  What ever these things you can do will help lower bp.

[aberdeen577]

Thank you, I will do this for sure. Right now my Mam is very ill and is going to leave us soon. This is not helping I am sure.

[Jeff912000]

You must lower blood pressure.  Otherwise you will get a stroke before you died of cirrhosis or liver cancer.
monitor BP daily.

Stop all supplements except for TNF.  TNF could also cause high BP  but you need it.  

sleep 8 hours a day.
execrcise everday to lower bp. run 5km a day if needed.  
eat whole grain brown rice.  The red coat is antihypertensive.  i take it every day.  
Eat very very little meat.  Eat only fish and a little chicken.
eat less salt.
lose more weight.  

do not drink alcohol
All these things lower BP in an addictive fashion.



LAstly take ACE receptor blocker only if these steps fail.