not commercially for all because they have patents until 2017 or longer (although i ve seen trials around the world and tdf and etv patents seem to be illegal or illegally prolonged over the years)
in any case just think about long term lamivudine responders (those that never developped resistance), after about 13 years they got hbsag and cccdna from und to extremely low so tdf might be able to do such more more over 10-13 years time and with no resistance for sure
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