Hepatitis B Community
cure!!!
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This forum is an un-mediated, patient-to-patient forum for questions and support regarding Hepatitis B. Topics in this forum include but are not limited to, Causes, Diagnosis, Family and Relationships, Living With Hepatitis B, Research Updates, Treatment, Success Stories, Support, Symptoms.

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cure!!!

s hepatitis b cn be cure nw a days?
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Avatar_m_tn

yes interferon+tenofovir or interferon+entecavir has a cure rate of 40% in 48weeks if hbvdna was already undetactable from long time

starting interferon+tenofovir directly with hbvdna detactable has a lower clerance rate of 26% in 48weeks
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Avatar_m_tn
in same situation of HbeAg- then still chances are 40% when dna recently UND?
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Avatar_m_tn
in same situation of HbeAg- then still chances are 40% when dna recently UND?
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Avatar_m_tn

40% is in hbeag negative, hbeag positive should have higher percentages but as you know if you are already on a potent nuc for 1-3 years you get probably hbeag neg by the time you add interferon

anyway add on of interferon from stable nuc with hbvdna und makes 40% clearance by 48weeks and extremely low hbsag in the remaining which are continuing therapy and proabbly clearing by 96 weeks.

only 1 patient on lam+adv was non responder, maybe use of etv+tdf could make him responder
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