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cure!!!
s hepatitis b cn be cure nw a days?
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yes interferon+tenofovir or interferon+entecavir has a cure rate of 40% in 48weeks if hbvdna was already undetactable from long time

starting interferon+tenofovir directly with hbvdna detactable has a lower clerance rate of 26% in 48weeks
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in same situation of HbeAg- then still chances are 40% when dna recently UND?
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Avatar_universal
in same situation of HbeAg- then still chances are 40% when dna recently UND?
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Avatar_universal

40% is in hbeag negative, hbeag positive should have higher percentages but as you know if you are already on a potent nuc for 1-3 years you get probably hbeag neg by the time you add interferon

anyway add on of interferon from stable nuc with hbvdna und makes 40% clearance by 48weeks and extremely low hbsag in the remaining which are continuing therapy and proabbly clearing by 96 weeks.

only 1 patient on lam+adv was non responder, maybe use of etv+tdf could make him responder
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