HBeAG positive/ AntiHbe positive ?!

[melcul]

can anyone with some backround in this hepatitis , can tell me what it means if I have discovered that I have hepatitis, but I have both HBeAG positive/ AntiHbe positive ?   almost everyone has one of them negative, but I don't.
thank you

[stef2011]

you can have anything and it has no meaning as to number infected cells, clearance of infection and immune system/host balance

i started hbeag neg hbeab neg, hbvdna negative in childhood
hbeag pos/hbeab neg, hbvdna detectable in the 20s
hbeag neg and hbeab pos rest of my life

does this have a meaning?no
does it have any impact on the status of the infection?no

hbsag quantitative is the only test to reflect number of infected cells, clearance of infection and chances of clearance of hbv by peginterferon.all the other tests dont

[melcul]

Did anybody had both hbeag and antihbe  positive and know what they mean?

[stef2011]

looking at hbeag positive or negative is totally useless, it was the 2000 and earlier view to consider it when we had no hbsag quantitative and little knowledge of the infection

[luckyman316]

Refering to this link may help you, but I don't see a reference to both being positive...

http://labtestsonline.org/understanding/analytes/hepatitis-b/tab/test/

[melcul]

I am sorry for my nonsense. I read a lot about hepatitis this past weeks but I didn't came across my situation with both HBeAg and anti Hbe positive.

for some reasons I don't have anti hbs in my blood test.

here is what I understand or I think I do : after acute hepatitis, if you don't get cure, it gets chronic. after that the first phase is seroconversion, or what is happening to me having both positive ?

hope to make sens now.

[StephenCastlecrag]

You are asking questions that do not make sense. Please visit website such as www.hepb.org or even here at Medhelp to learn more about hepatitis b.
HBeAg seroconversion is just a technical term to describe the transition from HBeAg positive to HBeAg negative. During the first phase of the infection,  we are always both HBsAg and HBeAg positive, and both HBsAb and HBeAb negative.

[melcul]

I asked this because I learn that you can have hepatitis all your life and not know it. and go when you have chirosis already or liver cancer for example  or anything else...and I wanted to know..if this seroconversion can be present in final stages .

[StephenCastlecrag]

It does not matter how long you have the infection. During HBeAg seroconversion, usually HBeAb turns positive after HBeAg turns negative, but for some, they may have both HBeAg and HBeAb positive simultaneously for a short period of time. Eventually HBeAg will become negative.

[melcul]

this is possible ....after the acute hepatitis became chronic or after many years of hepatitis ? because I don't know for how long I have it
thank you for your response .

[StephenCastlecrag]

You are most likely in a transition phase , eventually your HBeAg will turn negative as you have HBeAb already.

[melcul]

for what I read about it ...HBeAG must go negative, and Anti HBeAg must remain positive ?

In old chronic hepatitis for example, is it possible for both to be positive ?

[melcul]

so, it is ok if it stays both positive ? doesn't have to go negative one of them?  or what is the best possibilite in hepatitis B ?

[andrey19]

HBeAg is the hepatitis B envelope antigen, and anti-HBe are the antibodies produced against this antigen. If HBeAg is detectable in a blood sample, this means that the virus is still active in the liver (and can be transmitted to others). If HBeAg is negative and anti-HBe is positive, this generally means that the virus is inactive. However, this is not always the case. Some people with chronic hepatitis—especially those who have been infected with HBV for many years—may have what is known as a “precore” or “core variant” mutated form of HBV. This can cause HBeAg to be negative and anti-HBe to be positive, even though the virus is still active in the liver.

http://www.hepmag.com/articles/2511_18747.shtml