two years before my DNA was 133 IU/MI in 2014 May ,in 2013 it was 2500iu/ml. in 2010 after my daughter birth it was 20iu/ml Alt And Ast keep rising after my daughter birth,Hbsag quantitative was 1439 iu/ml 3 years before.
My mother and all brother and sisters are HBV negative.
Hi there, it's good you have the diagnosis. Did you see a specialist, they'll be able to tell you if you need to take a treatment depending on you full blood test results.
As far as I am aware pregnancy shouldn't be an issue at all.
Hi,
You wrote: "As far as I am aware pregnancy shouldn't be an issue at all". I think there is a high risk of passing the virus to the fetus if the mother is HbeAg positive and a high, >2000iu/ml hbv viral load. However the risk could be dramatically reduced if the newborn is given Hepb immune globulin and hbv vaccination within 12 hours after birth.
The term "fetus" should be corrected by "newborn" in the above message.
Yes, you can, of course, have more kids after eventually starting antiviral therapy. So far, based on limited experience, the drug tennofovir is prefered for hbv positive pregnant women on treatment, because it has low resistance and its safety to the fetus is better than other antivirals.
because it has low resistance
tenofovir doesn t have low resistance, it has no resistance whatsoever in any case
You are in a grey area regarding whether to treat or not. Your hbvdna is fluctuating and seems to be rising. Your ALT is slightly high for a female ( F2 fibrosis. I suggest you repeat your liver function test(ALT, platelet count, etc), hbvdna, HBsAg in the next few months. The results may clarify the picture, one way or the other. I assume you are HbeAg negative.
Just my opinion.
Hi StephanCastlecrag,
In actual ,, per doctor recommendation I should not be starting the medication for now. But I want to start the medication. I am HbeAg negative. But I want to start the Medication . On my insisting , Dr told me to start with Baraclude 0.5mg (Entecavir) . Should I start this or should go for Tenofovir ????
What is the major difference between the two ???
My alpha Feto protein is 3.5 ug/L
What I wrote was a citation from a research paper here: http://www.uptodate.com/contents/hepatitis-b-and-pregnancy#H231281766. However, "no resistance whatsoever" is even better than "low resistance"; so no problem there.
Below is a not so good news about possible resistance of hbv against tenofovir in previously entecavir resistant patient. But this could just be an isolated case.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085295/
My Doctor has told that my insurance company does not cover the medicine. So where can I reliably buy the medicine online ????
I am planning to go for Tenofovir . Is there any side effects for this medicine on the kidneys ???
I am already taking Vit D3 10000/iu , 1 softgel daily. Is there anything else recommended ???
I would wait, I m not a doctor, when you are hbeag-, it doesn't mean you need to go in treatment as soon as you are above 2000iu.
Have you had a liver biopsy done?
Family history of HCC (liver cancer)?
Do you drink or smoke?
What is your hbsag quantitative (in IU/ml) ?