replicor

[tinknocker]

So what was the outcome of Replicor..Any results?

[sorte]

btw, do you think Rep 2139-Ca may be used for HBe+ mainly or HBe status doesn't matter so much ?

[sorte]

exactly, fast track ! like here
http://www.healio.com/hepatology/chronic-hepatitis/news/online/%7B09e99bec-adf3-4539-9812-b30f66a3096c%7D/fda-grants-fast-track-designation-for-hdv-inhibitor

[Royal36]

Hope they will get now investors and Fasttrack approval from the FDA.

[sorte]

studyforhope: so cure for HDV is "just" lower/remove HBsAg ?

[mike9111]

Do you think replicor will ever see the light?

[studyforhope]

From the news article " Treatment was once daily via 2 hour IV infusion. Researchers measured viremia, hepatitis B surface antigen (HBsAg) and anti-HBs every 2 weeks using standard assays."

Very incorrect information. The treatment is once weekly, not daily.

Interesting to see that hausecker, who reacted silly and naive a few month ago, when I alerted him to the impact of replicors data on his iRNA predictions is now changing course.

The real big news is the dramatic reduction in HDV viremia in all patients who reduced hbsag. This points to a fundamentally different mechanism of Hdv virion reduction compared with HBV, more profound and more direct acting, with huge consequences for a disease that is rapidly progressing and currently almost untreatable. It will clearly be of great help to replicor to move forward.