to those who have chronic hepatitis b who cleared the virus, please i need advice...

[aderts]

what should i do to clear the virus??
my hbv-dna is 200,000 copies/ml..

right now im taking revovir.. is it enough?

[aderts]

is it okay for me to take godex?

since i dont have money yet for the therapy, ill just take godex... my doctor prescribed me this 2 times a day... he said that its for liver protection...

[stef2011]

since i have high viral load even with hbeag negative and hbeab positive.. does that mean that i have hbv mutations???
no, there is no correlation.we all have mutations but only some are classified and we know they are dangerous, the BCP and precore muattions are the prevalent form of cronic hbe neg and very common on hbe pos too

if i have mutations, does the chances of clearing the virus is very low???
no they are the same for BCP and precore mutation
only mutations for entecavir or tenofovir resistance lower your chances of making hbvdna und.
All type of mutations have been found naturally in people that never took drugs only tenofovir is free for resistance both naturally before therapy or under therapy, i guess this is by far the most potent antiviral for hbv probably totally free of resistance, we are almost at the 4th year of hbv trials without detection of any mutants even in those with detectable hbv

[aderts]

since i have high viral load even with hbeag negative and hbeab positive.. does that mean that i have hbv mutations??? if i have mutations, does the chances of clearing the virus is very low???

[stef2011]

since you have family history of liver cancer (which is not curable) and even resection has bery poor life expectancy if hbvdna/precor and bcp mutation are detactable, you are not pointing at a hbv cure but you are trying to avoid liver cancer death if it will ever happen

it can be possible you will never develop liver cancer like you uncle but if you do chances of survaival with hbvdna detectable are very very poor.research showed that hbvdna und lower liver cancer rates to almost zero so this is your point.

precore and bcp mutations are very very common especially on hbe negative, so check for these mutations if you can because they are closely connected with liver cancer development, if one or both positive your hbvdna must be und

so in the end the first doctor was ok if it was you to ask for less expensive oral therapy, but if you can afford interferon go to the previous doctor and discuss interferon with her, it is the best choice as first therapy

is it okay to take the therapy even if my alt is low?
since you have high liver cancer risk it is, my sister was inactive carrier and did interferon with normal alt when about 19yo, she didn t make hbsag negative but seroconverted hbe negative/hbeab pos and hbvdna und.it was a very good choice and she prevented cirrhosis

are there any side effects?
ntz no sides, interferon yes but since you are young maybe you'll only have some flu synthoms at start, discuss interferon sides with your doctor

[aderts]

my other doctor prescribed me revovir, but you said that its dangerous so stopped taking it.. actually she prescribed me two choices... ORAL and INJECTABLEs( interferon)... she said that interferon is very expensive so i choose oral..

is it okay to take the therapy even if my alt is low? are there any side effects?

[aderts]

i did find another doctor, and he said that i am not a candidate for treatment since my alt is low.... and he said also that ill begin my therapy once my liver is already damage and that means that my alt should be twice the normal range...

wtf? so i have to wait for my liver to be damage and do nothing? why is that so?

i also had my liver ultrasound and alfafetoprotein results, and the doctor said that they're normal...

it says the liver is not enlarged. it is homogeneous in echotexture with no focal lesion. the intrahepatic ducts are not dilated. the portal veins are unremarkable.

conclusion:
normal liver sonogram..

Alphafetoprotein (ECLIA) <0.500 normal