12 week test results confused!

[hunapu]

I have Hep C Geno 2b. No liver problems. Very slightly elevated alt/ast before treatment, picked up in a cholesterol test. My VL was 2,300,000 when TX began in Sept.  At 4 weeks VL was less than 10 iu/ml, and I was tracked for 12 weeks TX.  As of yesterday (which was 12 weeks) my VL is up to 250 iu/ml using quantasure plus.  I'm very confused about these results and can't see/talk to gastro till appt. Did my VL really go back up? Is this a significant presence or below threshold of the test?

[MrsOckert]

I think you would have to wait to see the paperwork before anyone could give you a definitive answer.

Not to be a killjoy, but if you've had a breakthrough you could show undetected at week 4 and then have a higher viral load at week 12.

Can you call your dr's office and ask the nurse for clarification?  If it was me the unknowing would drive me insane.

[GoofyDad]

Makes sense, doesn't it? Pre tx VL's jump all over the place. So, why not as you're crossing that threshold into Un-Detectable?

[cougareyes]

My 24 wwk pcr comes up next week, I was undetectable at 12 weeks. Just for reference I would have liked to have gotten a 4-wk; my doctor said no and at the time I was so beat up with sx, I couldn't fight him.
Since usual testing is at 12 wk, we really don't have alot data tracking more frequent pcrs. I've heard of incidents where a person was undetectable at 4 wks, a rise in vl at 8 wks, then undetectable again at 12 wks; then stayed clear.
So my question is: could there be more ping ponging of the vl in the earlier weeks of tx, like a battle that keeps changing fronts; until there's a winner.    Peace

[hunapu]

I guess I was not totally cogent.  I was told that because I was type 2b that if I had evr at 4 and 12 they would discontinue tx after week 12 since svr is statistically the same for those with VR 24 weeks and those at both 4 AND 12 weeks.  

All tests were ordered by the same gastro and done by Labcorp, Kansas City.

Baseline lab 2,332,000 (August 18)

The 4 week lab said <10 iu/mL

I have not seen the 12 week lab (Dr. got results yesterday and nurse called) but they said they were 250 iu/mL.  

[FlGuy]

Re-reading your post it seems like you've had 3 pcrs, pre-tx, 4 wks and 12 wks. Were all 3 at the same place and did all 3 perscriptions order the same test?

[FlGuy]

You said you were 'tracked' for 12 weeks. Did you continue the meds for those 12, and on schedule?  Are you still on the meds now?