3 month post tx test results

[carolhab]

Hi - have not posted for awhile, but just got my 3 month tests back.  I am(was?)  1a, about 3 mill viral load, on 48 wk trial of interferen and either viramidine/riba.  Still having sides, mostly fatigue and brainfog/depression, but slowly improving.  This test was done by an outside doctor, because it is not part of the protocal of the trial

HCV load bDNA   result <615
log10  RNA      result <2.79

along with a note saying my viral load is normal  

I assume this is very good news, but need opinions..  also, does anyone know the chances of being permanently clear, when 3 months out we are clear?  I am so cynical and don't want to get my hopes up, it's hard for me to accept good news!  Makes me realize how hard this struggle is, living with this for so long (for me, about 20 years) and the toll it takes on all of us..
thanks
Carol

[jmjm530]

Goof said: As I read it, 14% of EOT TMA negs will relapse. Thus 86% will not.
------------------------------

I'm not saying it doesn't say that -- frankly I'm too fried to look at it again LOL -- but it can't be that simple. What about EVR? Treatment length? Histology? Does this mean that a late-responding geno 1 who doesn't become TMA negative until week 30 -- and only treats for 48 weeks -- will have an 86% chance of SVR?

The Drusano model comes up with a similar SVR percentage, but only after adding 36 weeks of additional tx after the non-detectible point.

-- Jim

[bobbyullc]

SORRY,

ONE OF THE MOST PREVALENT SIDES IS BRAIN FOG AND I ATTEST TO THAT. GOOD LUCK
PS THAT IS A REAL POOR TEST TO USE IF IT ONLY GOES TO 615,MY TEST WENT TO 75IU AND WAS ONLY $248.

[bobbyullc]

THAT READING OF  2.79 EQUALS THE COUNT OF 615 VIRAL.
YOU STARTED WITH 6.48 AND DROPPED TO 2.79 A 3.69 DROP WHICH IS A LOT BETTER THAN THE 2 LOG DROP NEEDED. YOU ARE DOING WELL.
THE TEST PROBABLY WENT TO 50 BUT YOU WERE ABOVE THAT.LUCK.
BOBBY

[bobbyullc]

SORRY BUT JUST TO BE CLEAR.
YOU PROBABLY HAD A SENSITIVE PCR TO 50 OR 75 BUT YOUR RESULTS WERE 615 OR 2.78 LOG. NOT UNDECTABLE BUT NOT BAD FOR STARTING AT 3 MIL.

[carolhab]

Sorry guys I should have been clearer...  I finished my 48 weeks in Nov, so I am 3 months post tx.  Thanks for all the great input, I want a TMA 6 months post, I think.  Right now my plan wouldn't change much either way if I was totally clear or not,  but at the 6 month mark, I definately want to know if I am really clear so I can explore other options if I have to - so I will hold tight until then, but it sounds poitive so far... In the meantime, I hope this gives other 1a's hope that this tx does work for some of us, and not to give up!!!

[carolhab]

Bobby the results say that my results are less than 615 and 2.79, not that they are 615 and 2.79
thanks