For me, with Dr. Gish, as a proven acute, 12 weeks was not an option.
Initially, he told me 48 weeks.
Once I reached the 24 week mark, he has eased off on the 48 week benchmark and we will "discuss q. 4 weeks".
A lot of the old studies say 12 weeks is the bench for acutes, but more recently, the thinking is more is better.
Sorry, the "cavalier" comment was intended for "Ala", not you. As stated, I was also quite cavalier starting treatment until the anemia cut my legs out from under me. Yes, Valtod's post was excellent.
-- Jim
As many here, I was told to take my ribavirin with MEALS not snacks. I suppose the reason being that the riba bioavalialibility studies were done with high-fat meals, not snacks; not to mention riba appears to be kinder to the stomach when consumed with an adequate amount of food. That doesn't mean that taking riba with snacks (as described above) isn't OK. Just not optimum IMO. And sometimes, you just don't have the appetite for a meal.
"Almost a bit cavalier, as you too have a tinge of that." Of course you are correct, probably a defensive mechanism in my case...Every once in awhile I'll slip, and think to myself, "do you realize how much riba you are ingesting, or what will be the consequences down the road"..
I thought Valtod's post about optimism and pessimism, human nature was one of the more interesting I've read in a longtime.....
Anyhow -alagirl, are going to talladaga? I went a few years back...what a blast
you DO NOT need to "pig out" prior to taking Riba - a cracker with peanut or slice of cheese is all you need - Some people in here ate bacon every day - Not a good thing to do!
In fact, my doc said I could take the entire daily dose (1200 mg/day) in one shot, if I wanted. The effect would still be the same. About a year after he told me that, a study was done on the saturability of ribavirin on dosing more than 2000 mg/day. Based on that study, probably not a good idea to take 1200 mg at one shot, as some may be lost to saturability. But if you wait at least four hours between doses, you should be safe with the amounts we are discussing here. I also don't recommend taking 1200 mg/day in one shot because of the BUZZ. I did it a number of times -- catch up on missed doses -- and it was quite a BUZZ.
-- Jim