72 week club

[Valtod]

Four months ago, when I was discussing with my GI extending treatment to 66 or 72 weeks, I told him that of all the people on this forum, who did 72  weeks, no one relapsed. Relying just on memory, I thought there were at least a dozen of cases that I can back up my claim with.

Now I've just searched the forum archives and I'm surprised to find only 3 people who did 72 weeks and can actually show 6-month post-Tx PCR for SVR: DoubleDose, Cuteus and Jaroman. Am I missing someone?

Anyway, here is a list of the 72 week club (nicks and end of Tx dates):
DoubleDose - 10/04/03
Cuteus - 11/15/04
Jaroman  - 10/06/06
NYgirl - 2/08/07
Sincebirth - 6/09/07
Bill1028 - 7/07/07
MustangShelly - 8/01/07
Kalio1 - 8/24/07
Valtod - 8/27/07
St. George - 9/07/07

And those on their way:
NYCMark - 66 of 72
BThompson4 - 63 of 72
Proactive - 45 of 72
zazza - 43 of 72
Wyntre9 - 37 of 72

Can you please correct and add to the list.

I'm not sure what exactly happened with Kalio1 and BThompson4. Also, Sincebirth (Darryl) never posted after the end of Tx. And Bill1028 did 76 weeks.

Please share your stories, stats, latest PCRs and post-Tx side effects!

For example, here's the story of DoubleDose:
http://www.medhelp.org/forums/hepatitis/messages/38781.html

Thanks,
Val

[nygirl7]

St. George unfortunately relapsed.
You didn't note down that Cuteus is SVR but she definitely is!

I personally think the newer bunch will have much higher rates of SVR.  With the new group - we now have the Berg and Sanchez Tapias studies. Med reductions have been almost done away with because the docs now know better. People are treating harder and sticking to the plan in a major way.

Prior to these two studies it was pretty much just a desperation move that these guys were smart enough to pick up on without any data.  Now, it's a real medical viable course of treatment.

You know..it's not going to be so hit and miss because it's a completely different course of therapy than guesswork.

Thanks for the list - clear and going strong month 11 1/2

[BThompson4]

Sincebirth and bthompson4 relapsed.  NYCmark recently did or will soon do three month pcr.  Revenire did 53 of full peg and riba and then 1/2 peg for thirty weeks with no riba, so he did not do the 72 week regimen.

[Proactive]

Updated list of Extenders:Tx completion date: results
(please copy and repaste-add/update etc.)

DoubleDose - 10/04/03----cleared--svr
layla - 7/14/04
mikesimon - 15/06/04 ---cleared---svr
Cuteus - 11/15/04
Jaroman  - 10/06/06
NYgirl - 2/08/07 --cleared--svr
Randalee - 3/01/07
Sincebirth - 6/09/07
Can-do-man - 07/20/07
Bill1028 - 7/07/07 - Relapsed - did 72 weeks + 4 week dose reduction
MustangShelly - 08/01/07 ---cleared -svr
Kalio1 - 08/24/07----cleared---svr
Valtod - 8/27/07
St. George - 9/07/07
bobk                --------------relapsed
revenire            -------------relapsed
sldb (98 weeks) ----cleared svr

Still treating..........update when completed please
NYCMark - 66 of 72
BThompson4 - 63 of 72
Bill1954 - 51 of 72
Proactive - 45 of 72
zazza - 43 of 72
Wyntre9  - 37 of 72
cruelworld - 37 of 72
FloridaMouse - 6 of 72

[willing]

two other old-timer names are bobk and revenire both of whom extended and relapsed. Bobk did abot two years, rev I can't recall but perhaps someone else will.

Anyone interested in 72 might want to take a look at a recent study in hepatology:

http://www.ncbi.nlm.nih.gov/pubmed/18046717

which tracked 112 slow responders at full-dose rbv, unlike the earlier studies.

Also it's worth digging through the abstracts of aasld'07 for a japanese study that reported positive results with 72 weeks.

Overall, the success rate for 72 on this board does seem much higher than observed elsewhere!

[DoubleDose]

You can add after my nickname:  DoubleDose  10/04/03  cleared  - SVR, along with the other extender SVR's.  I am a big believer in extending tx, if the profile of the treating individual fits the appropriate pattern.  I think the extension usually works for slow responders, especially if dosing is kept at maximum levels throughout tx.  Best wishes to all of you who posted on this subject.  I like to see the above sort of public record-keeping, and follow up.  It helps everyone out there see real living examples of tx strategies that have worked, for real people, not just statistics in studies.  Our forum can serve as a great sounding board for those new to HCV treatment and treatment problems/ challenges.  Hats off to all of you for the ongoing involvement and input.  The information disseminated is invaluable, and the discussions are always stimulating.  Lots of bright and concerned people to be found here.  

DoubleDose

[FloridaMouse]

DoubleDose - 10/04/03
layla - 7/14/04
mikesimon - 15/06/04 ---cleared---svr
Cuteus - 11/15/04
Jaroman  - 10/06/06
NYgirl - 2/08/07 --cleared--svr
Randalee - 3/01/07
Sincebirth - 6/09/07
Can-do-man - 07/20/07
Bill1028 - 7/07/07 - Relapsed - did 72 weeks + 4 week dose reduction
MustangShelly - 08/01/07 ---cleared -svr
Kalio1 - 08/24/07----cleared---svr
Valtod - 8/27/07
St. George - 9/07/07

Still treating..........update when completed please
NYCMark - 66 of 72
BThompson4 - 63 of 72
Bill1954 - 51 of 72
Proactive - 45 of 72
zazza - 43 of 72
Wyntre9  - 37 of 72
cruelworld - 37 of 72
FloridaMouse - 6 of 72

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