ANC drop again while on Neupogen, What's next?

[Healed24]

Yesterday I got some more bad news from my doc and I don't know what I should do next, so I'm hoping you guys can give me some advice. I'm on week 24/48 and since week 2 I've had problems with my ANC levels. After my first shot my ANC dropped to 200 (from 2000 before tx), so my peg dose was lowered to 135ml (I was on a reduced dose for 20weeks until my ANC levels stabilized with Neupogen). My doc put me on neupogen and my ANC increased to 1200 so last week he put me back on the full dose of pegasys (180ml). After one shot of pegasys at 180ml my ANC went from 1200 to 300. Now my doc wants to put me on Neupogen twice a week, and I wanted to know if anyone gets two injections of Neupogen a week? Also should I just let the doc decrease the dose back to 135ml and stay on the one dose of Neupogen, or should I try and stay on the full dose with the two shots a week? I'm really scared because I don't want to keep putting more meds in my body, but I don't know what to do. Also to make matters worst, I'm also on 40,000 Procrit and although my Hemoglobin levels were steady at 10 but they are starting to drop. My doc wants to add another 20,000 of Procrit, which would mean another shot and more meds (when it rains it pours). I'm starting to get really fed up with the whole tx and I really don't know what I should do (keep going or just quit). If anyone could offer any advice I would really appreciate it.

WEEK 24/48
GENO: TYPE 1A
VIRAL LOAD PRIOR TO TX: 208,000
WK 11 <10ML
STAGE 0, GRADE 0
WEIGHT: 130 POUNDS
PEG: 180ML (FOR NOW), RIBA 1000MG
HAD VIRUS FOR 7 YEARS

BROOKE

[nyhepc]

you're half way thru...already taking the procrit and neupogen...i'd continue.  i also have ANC problems, taking half doses of neupogen twice weekly but only getting peg 90. will go up to 135 next week and increase the neupogen as needed.  you've gotten this far, try to stick it out, think of the outcome!