Aa
Aa
A
A
A
Close
Avatar universal

Alcohol and painkillers

Ouote fron other thread " Drinking with HCV, on antidepressants is suicide on the installment plan.  Throw in Acetaminophen, you've hit the liver failure trifecta!

Wow this quote from another thread scared the **** out of me. I recently tested positive for Hep C and am waiting for the results from the PCR test. Meanwhile I  am heavily on Tylenol 3 by perscription for pain from my knee replacement surgery. I also havebeen perscribed percoset when the pain is bad. On top of this I have been drinking a bottle of wine several nights of the week. Does this sound like suicide?
12 Responses
Sort by: Helpful Oldest Newest
233616 tn?1312787196
ok, lost too ebtire blah blah blahs on how and where things are metabolized...not doing it again...
alcohol and anything bad
aspirin nsaids bad for stomach/bleeding
tylenol within limits
depending on the state of the liver and kidneys any and every drug is bad and that includes food even, just more metabolic work for the liver.
all things are relative. the liver doesn't work as hard with tylenol as some others...
and like someone said..there are always pure opiates inlatter stages.
right now, I'm on Ultram 2 or less a day....if I go beyond this it effects liver enymes and they go up.

the easiet way to try to understand drugs and interactions is to think of clorine and ammonia...separately they are both good cleaners, put them together, one puff and your dead.
the same can be said of various drugs especially when mixed with alcohol...it's like a cyanide bomb in your liver..everytime....enough said...no one in here wants a chemistry lesson...
Helpful - 0
315996 tn?1429054229
I drank hard at ski club outings and dance weekends but I quit July 4th and have never looked back. I could keep booze in the cubbard for months if I wasn't dancing or going somewhere with the ski club (drinking club with a ski problem). I know everyone is rolling their eyes at my rationalization but I ain't drinking again ever in my life. What knocked me out finally, however, was 6 days of hiking 9-14 miles a day in Glacier National Park, Montana. I wasn't drinking anything but I was taking cocktails all day long of Tylenol, Advil, and Excedrin (one of each every 2 hours). Man, I wish I had tested sooner.
Helpful - 0
Avatar universal
just had to say, excellent post - you said everything...
good entry.
Helpful - 0
264121 tn?1313029456
Drinking with HCV, on antidepressants is suicide on the installment plan.  Throw in Acetaminophen, you've hit the liver failure trifecta!
----------------------------------------------------------------------------------------------
A doctor at a teaching hospital I posted an interview from (Posted the link last night) said, "alcohol is like an aphrodisiac to hepc"  So yes, unfortunately the virus does replicate faster if you drink and if you are treating your outcome is so much more questionable that most physicians will not treat you if they know you are still drinking.

As to the antidepressants, there are some types of antidepressants that are not recommended for people with hepc but research as shown that wellbutrin and ssri's are fine to take with hepc and it is in fact recommended that in regards to undergoing treatment, people who are either A) prone to depression or who B) develop depression while on treatment begin antidepressant therapy.  This is due to the fact that interferon, for some reason, frequently causes and/or exacerbates depression in many people.

Now, as the pain medication.  Most physicians are fine with you taking a certain amount of tylenol or acetimenophen (sp?) daily with hepc and in treatment *IF* you do not already have a certain amount of liver damage (and I don't know what that amount would be for your doctor and since I'm not a doctor I wouldn't want to speculate, but you can talk to your physician about this issue).  But in general, if the liver damage is such that a physician feels that tylenol is an issue, opiates can be prescribed without tylenol in them.  You would have to ask your physician how much tylenol he or she is comfortable with you using every day given the state of your liver.  
Helpful - 0
Avatar universal
tylenol and alcohol is a very bad mix....this 'combo' trx can cause very serious liver damage..remember this if nothing else!
Helpful - 0
179856 tn?1333547362
You can get most painkillers without the tylenol in them or replace it with Ibuprofen but taking them every four hours or such is not a wise move...just take them as sparingly as possible.  If you've tested pos for HepC and your still drinking...it won't matter much how many tylenol you take. The alcohol will destroy your liver in record time on it's own.
Helpful - 0
Avatar universal
There are a number of studies that recommend avoid any acetaminophen with any level liver damage, and if you have HCV, you have 'some' level of damage.  Narcotics and alcohol are are bad mix.  You forget to do things, like breath!  You're really putting an unnecessary strain on your liver.  And if, God forbid, you have to go on a transplant list, one of the first issues addressed is what your drinking and drug use are.

Things to ponder............
Helpful - 0
148588 tn?1465778809
I think you've got it backwards. NSAIDs (aspirin, ibuprofen, Aleve) are the ones that have more of an effect on the kidneys. Acetaminophen effects the liver and can ruin it given a large enough overdose.
Helpful - 0
233616 tn?1312787196
the alcohol acts as a solvent pumping the painkillers into your system much paster, causing recreaction effects but also causing many more heart and respiration/overdose episodes.
  tylenol alone for yur joint may help with no codiene, and it is mainly the kidneys that metabolize it,

Yes it does sound like suicide for you liver at the very least. Dependancy on drug with alcohol is a vicious circle that can do much more damage in one tenth the time than consumming either one alone.

since pain killlers do metabolize in the liver, and raise liver enyzmes, I believe they should be kept to the lowest amount necessary to have some normalicy and times of comfort.

we all love to dance and run etc, and those things are hard to give up, but if you can;t find a safe compromise, like an activity not so hard on knees, and you are getting some addition joint pain on tx. then you really need to decide whats more important, getting my liver back to healthy so it doesn't explode in a painful death, or having a night out all loobed and doped up.

certainly if you reach SVL you may one day return to the excersise, and try some of the non-opiate type drugs to aide your joints. Condrotin, glucoamine, celbrex....many healthier choices are out there that are well worth trying before resorting to addictive opiates.  

I wish you well with this, probably it's the hardest part for many to come to....the realization that if they want their health back alcohol and pot especially cannot be part of their lifestyle anymore.
But not to worry, there's lots of folks out there that stay sober that do fun things. One just has to start looking for them.

BTW one pill with one drink make that pill between 2 and 4 times stronger, and the fast absorption rate is dangerous.  So if you take 2 hydrocodones, wash it down with 2 drinks,,,,you will be affected like you had taken 8 pills. this is why strokes and early heart attacks are on the rise. Folks don't know they are messing big time with their body, and in particular doing massive damage to the liver which has to try to neutralize all those poisosns so you won't die.
Here inPDX if they discover you are drinking, you'll be removed from tx.
so be careful you two!!
hope that helps
Helpful - 0
315996 tn?1429054229
I found out I had hep c because I was going to week long folk dancing events and drinking all day (rum in my gatorade, 8-10 drinks or more a day) and I had a bad knee(osteoarthritis) so I was taking Acetaminophen so I could dance longer (10 hours a day). I kept getting worn out and thought it was pnuemonia relapse and finally just had to go to the doctor and look for something because I was too wasted to go to work. Really upset I read the symptoms wrong and so late. Now I am waiting for my biopsy and million dollar blood tests to come back and have them phone me to come in and see them. Maybe I'll phone them tomorrow.

I would be asking if there are alternative pain killers for your knee replacement. I am defenitly no expert and yield to anyone that has something better to say. But I know the alchol and Acetaminophen changed me and my health.
Helpful - 0
186606 tn?1263510190
i have had several things during treatment that required oxycodone. they are free with it.
Helpful - 0
148588 tn?1465778809
Ask your doctor how much acetaminophen you should be consuming. Most say to keep it under 2000-3000 mg/day. Both T3s and percocet have acetaminophen in them, so keep track of your cumulative total. The wine is going to be harder on your liver than either the codeine or the oxycodone.
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.