Check this Out

[Rockerforlife]

This protese inhibitor trial i am signed up for is not the Vertex one..its the Boceprevir Phase II Study ....anyone out there know anything on this.,,,here s a liink to some news on it...looks really good


http://findarticles.com/p/articles/mi_m4PRN/is_2008_August_4/ai_n27967944

[Wilko1956]

What can anyone tell me about  Treatment-Naive patients with geno type 1a?
Does this Boceprevir have results posted anywhere for 1a?
What will it be taken with?
Sorry for the questions. If anyone can help I would apreciate it greatly.
I'm just not ready for another pipe dream.
Still I'm sure it will help most people.

[Rockerforlife]

with these number i think i have good odds....not the best but worth taking.... dint have too many choices here...its do or die

[Rockerforlife]

475 is the correct number...i just rounded it off...to make it esay to see the 2  logdrops...baseline...30,000.000
                4 week  ............300,000                      
               8  wk..................    3000
              12 wk.........................300

actual numbers i have if you want

[CoWriter]

I hope you won't get offended by what I'm about to say, but I'm sort of concerned.  Your thinking doesn't seem to be clear.

Earlier today you said that your viral load at week 12 was 300 and now you're saying that "at week 12 my load was 475"

So you're saying two different things.

And both Marcia and I had told you that since you didn't clear at 12 weeks....cleared at 24 weeks and you were still clear at 48 weeks....and the virus came back after....that makes you a RELAPSER.

And now, you're asking the same things you were asking before....all over again.  

"Well...i know im not a RVR...So what the hell am i..im not a nul responder...im not a non responder"

And the 74% SVR you're looking at again.....is the one for NAIVE patients.

Anyway....take care.  

[Rockerforlife]

So this what you posted apllies to people like me and you?...well thats good news isnt it?....what co writer was posting seemed like a death sentence...LOL...i dont care any more...im just gonna gett my weight down to 185 lbs by OCT an go for the BOC trail...and if i dont make it then...i   WILL go for the 72 soc....odds are my liver may reverse a step too....THINK=POSITIVE BROTHER

[can-do-man]

Were both RESPONDERS so we need to forget the null responder bit as it doesn't apply to us... So as slow responders who relapsed this is what we should be interested in.
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In a 48-week treatment regimen, the SVR rate at 12 weeks after the end of treatment (SVR 12) was 74 percent (ITT) in patients who received 4 weeks of PEGINTRON(TM) (peginterferon alfa-2b) and REBETOL® (ribavirin, USP) prior to the addition of boceprevir (800 mg TID) (P/R lead-in), compared to 38 percent for patients in the control group receiving 48-weeks of PEGINTRON and REBETOL alone.(1-3).
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What ever you decide i wish you the very best guy........

cando