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A new, large study finds that African-Americans diagnosed with hepatitis C (HCV) respond better to treatment when the antiviral drug, ribavirin, is dosed based on weight rather than standardized.


http://www.hepatitis-central.com/mt/archives/2004/12/weightbased_tre.html
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Being overweight and having fatty liver also have been shown in a number of studies to lead to lower rates of hepatitis C clearance in patients treated with interferon and ribavirin


http://hepatitis-c.emedtv.com/hepatitis-c/hepatitis-c-diet.html
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Also, African-Americans have high rates of insulin resistance and H. pylori infection (a stomach infection with a common bacteria) and both things lower SVR.

But insulin resistance is believed to be the biggest cause of why they fail Tx.  

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