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Avatar universal

HCV Tx success with 1b and cirrohsis???

Hi All,
   My first time here and I was just wondering if anyone has had successful TX with Genotype 1b, and biopsy results of stage 4, with extensive fatty liver? I'm now 16 weeks into treatment and am feeling pretty down about what I've been hearing about success rate for my situation. My GU said I have a 35-40% chance of clearing. Not very good odds. I'm just so scared and depressed. Have tried an Antidepressant but had a bad reaction and now I'm afraid to try another. Any words of encouragement would be helpful!!
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Avatar universal
Hey how's it going girl? hope treatment is being kind to you. Did you have a 4 week PCR?
Are you still with the doctor ( I remember him as Dr. You're too Pretty to Have Cirrhosis lol) and is he being helpful with your tx? Hope he is learning and listening to you.

Helpful - 0
92903 tn?1309904711
We are on the relative forefront of a leading edge medical treatment. Having computer models and 'odds' to guide them is what enables today's researchers to offer the treatments we currently have available, and to develop new. I will take an informed calculation of probability over a 'might work, might not', any day of the week. Being given tangiable odds was what empowered me to lob 26 weeks off my prescribed treatment, against the advice of many here who don't like thinking in calculated probabilities. When it comes to choosing a calculated, methodical, and logical approach over an emotional and uninformed one, I'm going to take the former every time.

But that's just me. Others will handle it in whatever way works best for them. Be well.
Helpful - 0
92903 tn?1309904711
I'm gonna watch what's happening to my liver, and the development of new antifibrotic therapies. I don't want anymore INF without a compelling reason. My doc expects improvement to take a long while, but as long as I ain't getting worse, I'm probably getting better. I know they don't mean a whole lot, but I had a seemingly improved U/S last month, which read in part 'no evidence of nodularity' and some other mumbo jumbo about non-remarkable echogenics or something. Same radiologist read my last several, so she was comparing, I think.

Anyway, from where I sit, I don't see a compelling reason to start up inf at this point. Have you seen studies comparing SVR and additional INF against SVR and no INF?

BTW, I'm still struggling to find all my mental faculties and I'd be loathe to beat on this poor half-broke thinker any more if I don't need to.

Take care.
Helpful - 0
92903 tn?1309904711
FYI, this is what the liverhead has to say about last U/S (he doesn't buy the assessment of 'normal' liver size):

As for the US, it is notorious for under or overstating size of the liver, but the fact they did not see nodularity or "increased
echogenicity" would be very reassuring for ongoing improvement of the histology.
Helpful - 0
92903 tn?1309904711
the odds are often beaten aren't they...

Not to be glib, but of course they are. That's the point. To mathematically express the chance they will be beaten. So the second number (the denominator) says, on average, defines the proportionate number of times the alternate outcome will be realized. So, 4:1 odds are going to be wrong 1 out of 4 times.

Take care.... I'm off for Halloween shopping.....
Helpful - 0
91778 tn?1252555170
Hey Kalio how are you doing? Yes I am with the same Dr. He has been out of town for the last 3 weeks.So I have only seen 2 times. But both times he was so busy looking at labs he never even ask me how I was doing. He will not do a 4 week PCR. Have to wait for 12 wk. darn it! I see him on monday. I did shot 9 last night. Its has been OK. No too many sides, just mainly fitique. Hope you are doing good. Take care, Debi
Helpful - 0
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