Hep C Trials of VX-950

[JER22]

Are there any trials of VX-950 now enrolling volunteers either in the US or abroad?

[can-do-man]

With some drugs and in early trials yes. I could be wrong but i don't think vertex is one of them.

[doglover28]

Do some of the people get placebos on trials?

[can-do-man]

Cuteus makes some very good points. Their guide lines are set in stone. Cuteus got me thinking and since i had insurance i talked to my hepo. Glad i did as most trials won't give rescue drugs. But lower the dose, and early on in tx. That might cause you not to have the 2 log drop and out you go. If you have little or no damage and want to go the new drug route i would suggest you wait till their trials our further along.

[doglover28]

I am glad I read your post.  Thanks for that info.  :)

[cuteus]

If you choose to do tx for hep c, and have  insurance that will cover it, I would do that before any trial. These trials have many restrictions and limitations and if you do not respond as per their expectations, they might drop you and you might  then be labeled as a non responder and unable to get in other trials. Research thoroughly how the trial is going to be held. whether they will drop you at, for example if you don't respond by wk 12 or will they continue you on? Will they use rescue drugs if needed or lower your doses, therefore lowering your shot at SVR? These are just some things to consider, there are more and every person should ask very specific questions before entering the study. You don't want to waste your time on something that will only benefit the researchers.

[doglover28]

Thanks!  Yeah, I guess she said that because I wanted them to schedule the biopsy before the next appointment. I must be getting a little anxious to get the show on the road.
Actually, it would probably be good to wait until the end of summer to start treatment if possible.