Treatment, and HCV, all had an impact on my menstrual cycle. In my first treatment I did have one or two "heavier" bleeds that seemed to last a little longer than usual, possible due to my blood being thinner whilst on tx. On my 2nd treatment my periods stopped altogether and haven't returned. As the liver is integral in the production of hormones this was not surprising to me. I believe I have had an early menopause due to having and HCV and treating HCV.
NO, should work the opposite since it reduces estrogen levels.