Grapefruit does not even affect the TX drugs ive heard and never does lemons...BUT...ive read some where that they may affect te PROTESE drugs
Thanks Rocker. Phew! Neither of my daily meds are on there. I love my grapefruit juice - drink it every day.
The following drugs are affected by CYP3A4 inhibition with grapefruit compounds:
The benzodiazepines triazolam, midazolam, alprazolam and quazepam[2]
Ritonavir inhibits CYP3A4 preventing the metabolism of protease inhibitors[3]
Additional drugs found to be affected by grapefruit juice include, but are not limited to:
Statins such as atorvastatin, lovastatin, and simvastatin with the exception of Pravastatin which is unaffected. [4][5]
Dihydropyridines including felodipine (Plendil), nicardipine (Cardene), difedipine, nisoldipine (Sular), nitrendipine (Bayotensin)[4]
losartan (Cozaar)[4]
The Cough Suppressant dextromethorphan
repaglinide (Prandin)[4]
verapamil (Calan SR, Covera HS, Isoptin SR, Verelan)[4]
Antiarrhythmics including amiodarone (Cordarone), quinidine (Quinidex, Cardioquin, Quinora), disopyramine (Norpace), propafenone (Rhythmol), and carvedilol[4]
Antihistaminic terfenadine
Cisapride which treat GERD
The male impotence drugs sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra)[4][6]
The anti-migraine drugs ergotamine (Cafergot, Ergomar) and nimodipine (Nimotop)[4]
Fluvoxamine (Luvox, Faverin, Fevarin and Dumyrox)[7]
Codeine and Tramadol. [8] It reduces the amount of codeine converted by CYP3A4 into norcodeine thus increasing the amount metabolised into morphine.[citation needed]
cyclosporine. Blood levels of cyclosporine are increased if taken with grapefruit juice. A plausible mechanism involves the combined inhibition of enteric CYP3A4 and P-glycoprotein, which potentially leads to serious adverse events (eg, nephrotoxicity).[9]
Omeprazole
Zolpidem (Ambien) Reports indicated users being only mildly effected. [10]
oxycodone[citation needed]
Quetiapine (Seroquel, Ketipinor)[citation needed]
methadone Inhibits the metabolism of methadone and raises serum levels.[11]
Psilocybin[citation needed]
Trazodone ((Desyrel) Reports have indicated users experiencing little to no effect. [12]
http://en.wikipedia.org/wiki/List_of_drugs_affected_by_grapefruit
Is it true that there are some other meds that should not be taken with grapefruit?
What is so special about grapefruits and the Seville oranges to make it possible for them to interact with medicines? The skin of the Seville orange and grapefruit contain compounds called furanocoumarins. When these fruits are squeezed under high pressures to make juice, the furanocoumarins are forced from the peel into the juice. These furanocoumarins can then prevent natural enzymes in your body called cytochrome P450 (or CYP450) from working correctly.2 The CYP450 enzymes are needed to break down certain medicines so that your body can get rid of them. When these enzymes are not able to work properly, certain drugs could build up to dangerous levels within your body and can cause many dangerous side effects.
I found some info...BTW...when i post something,,,trust me when i say ive read up on it,,this is not the same site as i was at before and that site was a hep site
It is highly possible that lemons and limes could be related to the pummelo and could cause the same type of food-drug interactions.2 Currently, more research is being conducted to determine if any of the other sour citrus fruits can interact with medicines.
http://www.consumer-health.com/services/cons_take14.htm