Opiates

My dr. prescribed percocets for pain...bone, primarilly. Last cbc showed elevated enzymes. I dumped quite a few into a puddle of liquid on kitchen counter and didn't pick up a script 2 weeks ago...oh well. I am wondering if this has to do with the acetomenophen...raising the enzymes. I feel pain more intensely since doing double dosing -2 shots a week. I've done anti-inflamatories and otc stuff. When the pain is there nothing that can get me outta bed and to work but opiates. I would like to try it w/o the acetomenophen as we know can cause liver inflamation (inflammation). What else can I ask for? Ultram...useless. I don't know. Can one get demerol in pill from? What's the next step up from percocet w/o acetomenophen? Is anyone taking stronger opiates and what are they and are they helping w/sx?

[merryBe]

they told me Ultram could not affect the liver.......wrong.
I went off it for a week, and enzymes returned to normal, now I take 2 a day, not the 8 that were prescribed (which can give seizures)....and enzymes are still normal having cut back.
however pain control is far from optimal of late.
I'm not sure I'd trust any standard safety knowledge on any of this stuff.

you may want to read the whole data for each drug especially as it relates to children and the elderly and clearance/organ damage issues. this is because when you have loss of function, it's like reducing the size and/or capability of your liver and/or kidneys. that means drugs stay in you longer and cumulative damage becomes an greater issue.

people have said opiates alone are safer, but they are certainly not without some risk as well, to heart as well as other organs.
the best advice is to keep to a minimum for comfort any drug, and read up on the literature yourself, and talk to your hepatologist and pharmacist who generally have greater knowledge of drugs and your disease than a GP would, absolutely do that.

deep bone pain is one of the hardest to manage, I would definitely tell you NOT to use a fentenyl patch, they are very dangerous for overdose. there is both a time release morphine sulphate and the more expensive oxycontin that have better safety value and give you a steady dose state that is lower overall than 3-4 hour pills but tends to control pain better because there is no rebound effect (greater pain as they wear off). they last from 8-12 hrs per pill. If the pain is constant this would be something to consider.
If it's occasional pain, stick with the as needed thing, smallest dose that will work, not with added things that don't really touch the pain.
docs only object to this unless you have a history of recent drug abuse, but even then, with this disease, they seem more willing to medicate.

[desrt]

You can get straight painkillers but they're going to work better compounded with an anti-inflammatory (vicoprofen instead of vicodin, for instance). Is there a reason why you can't take NSAIDs such as aspirin or ibuprofen? It's doubtful your doc will prescribe oral demerol for tx related sides, see if he will Rx your oxycodone either plain or compounded with an NSAID.

[ladywhy]

Thank you both. I'm going to see Dr. tomorrow. My liver enzymes are up....and I'm now concerned with taking tylenol.So I'll see what he has to say.

[Susie2007]

I have oxycodone which is percoset without the tylenol. However, while it works, it does not work as well as percs with tylenol.

[Myown]

I hope you feel better. Thats crumby that you are feeling pain. Let us all know how you make out at the doctors tomorrow.

I better be going to bed soon. Its 11:38pm. I don't know why I am staying up so late lately. I like going to bed before 11:00, but lately its not the case.

[merryBe]

well I just ended up in the same boat as you, severe jaw pain for 4 days...and docs were all out of town so nurse called in 5/500 vicodin/tylenol.....which worked for 15 minutes and then I had to take a second.  then today, pain all gone.
this is the weirdest most annoying symptom yet (well not counting the itching) because it comes and goes. One day the ankle flared up, and I couldn't put any weight on it...next day, like it never happened.
I think the interferon is the main culprit on this, could be wrong....which med are you double dosing and did they explain how this can so over stimulate the immune system it can set off autoimmune stuff, like RA etc. I assume you know this if you are already double dosing...but maybe there's some happy middle ground? like a dose and a half...because you don't want to push your immune system into attacking it's own tissue and marrow etc. I think it's the IMG...immnoglobulins test that will clue them as to if this is happening...but you need the blood work to find out what is happening, and not just to mask a pain that may be clueing you to some real problems...(I did that for a while, and it only led to more serious problems, but I didn't persist in getting help for them..because they had me too doped up. Just a cautionary to cross your T's here.

[sunspot]

Mepergan Fortis Oral
This combination medicine is used to treat moderate to severe pain. Meperidine is a narcotic pain reliever similar to morphine

I used this after my oral surgery. I've heard it compared with Demerol

[desrt]

Mepergan Fortis = meperidine = Demerol

"A rose by any other name..." would still be unusual to be prescribed for treatment side effects unless you had other fairly serious pain issues going on at the same time.

[nygirl7]

Yes Meperidine is demerol.  Not many docs would hand out demerol for our hep pains. Percocet or Darvocet but Demerol usually isn't for long term pains because it's very addictive.

[nygirl7]

Oh PS There are two different strength Percocets 500 and 750 I think..maybe you could get the stronger one rather than the regular one?