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Please help for proper diagnosis!

1. On 22.06.08 my mother had an anti HCV test which told non reactive (Cut off Value 1.00 patient value .46). After that she had blood transfusion on 07.07.08 for operation and the blood were tested for anti HCV and result was negetive.
2.On 06.07.08 she had operation of uterus and then the biopsy report said cancer.
1.Again On 20.08.2008 my mother's blood test shows that her anti HCV is reactive. It said cut off value 1.00 and patient value 2.56. As the HCV rate was close to cut off value it was suggested to have the test again.
2. It is needed to tell that my mother is suffering from Endometrium adenocarcinoma (cancer) reported after operation.
3. On 27.08.09 mother had her first chemo for cancer traetment.
4.Again on 17-09-08 her blood was tested for anti HCV and it said negetive (cut off value .20 patiemt value 0.7 ELISA on method)

Now my query is which I should consider true?

If it is  considered that the first report(negetive) is true and then after blood transfusion she had HCV (wish to Almighty that this should not be) then is it possible to get the accurate result just after 40-42 days which tells positive? Again after 30 days of 2nd test report it says negetive.

Please help me giving your opinion about the incident what might be the right thing.
1. How long it take to get accurate result after getting infected with HCV.
2.Is it possible to get movebale hard pie sized swollen lymp nodes under jaw line within 40 days of getting infected with HCV?
3. How minimum time it takes to recover from HCV after getting infected.

Please help me!!!Please...
12 Responses
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Avatar universal
help plz!!
Helpful - 0
Avatar universal
is it possible that as she is taking chemo treatment for cancer the immunity is low and anti HCV is not grown upto cut off value??
Helpful - 0
Avatar universal
thanks everybody for such nice sharing. Total 4 test performed in 3 labs. Ne way, i wud do it again after sumtimes again..and hope it should be negetive blessed by GOD...
Helpful - 0
233616 tn?1312787196
HCA is right, her initial test was a false positive.
chances of getting HCV from transfusion 1 in 600,000

chances of getting a false positive 1 in 10 in some labs.

these machines a HIGHLY sensitive, but are dependant on the fastidiousness of the lab tec. Slide contamination happens often...in which case the computer doesn't know that the prior slide left particulate, and the next slide is read as positive.

My sons 1st two test were positive....next 2 neg..
finally labcorp did the >1 test...said he was negative and NEVER had any antibody found no RNA, no genootype...ergo he never had it....but the machine, sensitive to parts per million wasn't kept clean and so 27 virions from the prior slide ended up on his slide.

make sure and use a different lab for confirming tests. Best to your mom.

mb
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Avatar universal
I wud also like to think that mother never had Hep C. The positive result was false one.Thanks everybody for ur concern and kind reply.I did not know that if once positive and recovers automatically then anti HCV wud be alwys positive!thanks all..
Helpful - 0
179856 tn?1333547362
Makes sense to me I wasn't really thinking but you are 100% right (as always) HCA.
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Avatar universal
HCA
I can tell you 100%- she never had it!!!!!!!!!!!!!!!!
Anyone who clears spontaneously will  still  test positive for antibodies..
Helpful - 0
179856 tn?1333547362
Shawon it seems as if she does not have hep at all, she could have had a false positive or she could have been one of the up to 20% that clear it on their own but - I'm in no way to know which is true but...be relieved it doesn't appear that she has it.

Good luck I hope the rest fof the situation resolves as easily!
Helpful - 0
Avatar universal
Another test was performed.It also telling Negetive.
Was she infected anytime and recovered automatically or never had it,the positive reult was a false one??
Helpful - 0
Avatar universal
thanks all for ur concern. I hope that mother should not have Hep C. all tek cr
Helpful - 0
Avatar universal
HCA
Your mother,as  far as can tell,does not have and has never had Hepatitis C Two out of three tests showed negative for Hepatitis C antbody.The third was inconclusive.
She has a cancer in the lining of the uterus which would in any event be unconnected.
The symptoms you describe do are not consistent with Hep C.

I think you have read that it can be aquired from blood transfusions as she had one recently she may have been infected.

All donated blood and blood donors have been screened for Hep C for many years now.

Hope this helps you as you have enough to deal with from the cancer problem.
Helpful - 0
Avatar universal
I know it is very confusing and scary knowing your family member might have Hep C. Here is the following information I have of Hep C. I hope this helps.

Many people do not experience any symptoms when they become infected with Hep C. Symptoms may emerge later, taking anywhere between 15 and 150 days to develop. About 15 - 40% percent of infected person clear HCV within the first six months of exposure. If unsuccessfully get rid of the virus, infected person will gone into chronic Hep C phase. Chronic Hep C will not go away on its own. In most people, it is a slowly progressive disease. People with chronic Hep C are at risk of developing cirrhosis, liver failure, and liver cancer. But remember, many have gone living a healthy life for 20,30, or 40 years with the virus.

Symptoms may include:
- a short, mild, flue-like illness.
- nausea and vomitting.
- diarrheoa.
- loss of appetite.
- weight loss.
- jaundice
- itchy skin.

Based on Dr. Melissa Palmer's book, she suggest 10 days to 6 weeks after exposure, HCV RNA needs to perform on the exposed person. Multiple determinations of HCV RNA are required to confirm infectivity, since the level of HCV RNA waxes and wanes after infection. For example, HCV RNA may drop to a level beyond detection, but this does not necessarily indicate that person does not have HCV. and one positive HCV RNA result does not definitely confirm acquisition of infection.

I know it is hard right now but think positive. I just experience this fear the last month so i understand your concern. Just perform more test to confirm this. It could be false positive.

The second blood test show i am Hep C free. I will test again in 6 months to double check the result. All doctor seems to think I got at it at birth. So think positive!
Helpful - 0
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