Does anyone know how long or when your liver begins to heal . Is it during treatment ? or does it take more time? I am geno 1b grade 3 stage 2 pretreatment. I am undectable since week 4 of treatment . I am in week 15 of treatment now.
I belive the healing begins when the cause of the inflamation is removed, I.E. the virus, alcohol ect. The amount of healing depends on whether a relapse of either happens. The liver is extroidinary in it's ability to heal and one of the largest organs in the body, and only a portion of it has to work properly to make a large difference. Interferon has been shown to have a positive effect on healing the liver, but if it is because it slows or stops the virus from entering the cell for those with a maitenance dose or tx who knows?
is that right? sounds like there is no real downside to tx. except for the sx , that is. and then, that seems to vary from person to person. hearing that makes the decision to treat even more compelling. even though i decided to treat already. thanks for the input.
Also - taking interferon GREATLY reduces your chance of getting liver cancer, and that was one of my biggest reasons for doing treatment. I know a woman battling liver cancer who has HCV and didn't treat and well - it's NOT the disease you want to get because it's pretty much fatal.
There are a LOT of pro's to doing treatment - which is why I am an avid suppoorter of trying. The sides suck - yes = but not more than terminal cancer.
No studies here, but anecdotal reports from the clinic where my VX trial is running.
Seems they were skeptical of improved histology post-svr. However, they say they are now watching it closely in their patient community and are seeing significant improvements. No sure what proportion of the population this suggests, nor the inital conditions of these cases.
Just re-read my previus post and I think I wasn'r clear. Combo therapy is a lifesaver, no doubt about that. And it's appropriate for many of us. But I would be cautious about thinking of it as a promised path to immproved histology. Anyone have any studies on the likelyhood of fibrosis regression with SVR vs. w/o SVR? That would be pretty interesting, I think.
Milk Thistle (Siymarin) is supposed to help with regeneration of the cells:
First silymarin stabilizes and strengthens liver cell walls, stopping toxins from entering. It acts by inducing formation of liver cell proteins, which are incorporated into the cell walls, making them stronger and more resistant to toxins.
Second, by increasing the rate of protein synthesis, silymarin enhances regeneration of liver cells.
Third, are the antioxidants and free-radical scavenging abilities of this marvelous weed. As if these impressive effects weren't sufficient, the fourth mechanism silymarin gets involved in is the enzyme and catalytic activity of the LIVER. It inhibits production of the enzymes which produce substances damaging to the liver, while at the same time preventing the depletion of glutathione on liver cells, a substance which mediates cell metabolism
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