Triple TX length. Anti-nausea/ rash

[Cory255]

Got the dreaded rash on elbows, knees, & feet wk 7 on Incivek, Pegasus (alfa-2a), & Copegus.  

I've tried the following, any interactions with these and incivek?

Hydrocortisone Anti-Itch Cream - Cortaid Brand
Maximum Strength Cortisone Hydrocortisone Anti-Itch Cream
Diphenhydramine HCI 25 mg Anthihistamine

Geno 1, starting viral load 2,230,643.  Wk 4 VL not-detected.  I need advisement on # of wks I need to do?  

Previous TX - 09' - 44 wks w/ Peg-interferon alfa-2b & Ribavirin.  Cleared ( UND ) @ wk 12 - relapsed 1 month post TX.

Also, I was prescribed Promethazine 25 mg, generic for Phenergan for anti-nausea.  Any interactions w/ incivek?

[Cory255]

You told your Dr. about the Fluocininide.  How'd you find about that?  At next meeting, I'm gonna try to get a rash prescription.

[Cory255]

Thanks for the trustworthy info.

[Ironpony]

I have both.. zofran was no longer covered (but I got a huge bottle to start with, so they prescribed promethezine. The promethezine does not touch my nausea. I am hoping I have enough zofran to get me through. I occasionally get a headache but it is worth it to not be nauseated all of the time!

[ceanothus]

That's right. They were both being extremely conservative about what medications they would allow me to use while on the Incivek. They said that Ondansetron (generic for Zofran) was the safest anti-nausea pill to take with Incivek. They also insisted that prior to starting tx I had to change my AD from Zoloft to Cymbalta (though in this case Cymbalta was not the only AD I could use, just their first choice in my particular situation). I really was extremely impressed with how well the Ondansetron worked - it took effect in about 15-20 minutes, had no discernable sx at all, and took me from vomiting to actually feeling good enough that I had a little bit of an appetite. When I had tried Promethazine in a previous round of 2-drug tx, I had not found it nearly as effective and it really knocked me out every time - I never did acclimate to it. I'm really glad it works well for you, but you might want to ask about the other drug just to be on the safe side.

[BoceprevirGal]

Hmmm, I am on Victrelis, and so I think the Incivek rash is different from the common riba-rash~
   I got a rash last week, and at first I did try Benadryl, but read that it was dehydrating, and since I'm never able to drink the gallon of water we are supposed to drink (I drink maybe half of that, I think), then I went to my Doctor, and had her prescribe me some anti-itch pills called Hydroxyzine.
The Doc looked it up on her pom-pad and there was no interactions with my three meds, so you could check, to see if it is safe with, Incivek. I took the pills every 6 hours, and they did help a bit. But I have to stay out of the sun, or the rash comes back~

[Dawn703]

First time I got the rash, Eucerin calming cream worked. Benadryl, hydrochortosone did not. No drug interactions there. I currently have rash again, and NOTHING worked. I finally TOLD my Dr. To prescribe Fluocininide. Again no interactions there. It has worked great. It is not completely gone, but is subsiding and itch is so much better. Don't know about drug interactions for your antinausea, but Zofran works great, it causes annoying headache occasionaly but no drowsiness.