Extreme levels of GGT, AST

[Graver13]

hey doctor,

I have had elevated liver enzymes for a while, I share it with my brother, mother, and an aunt but not from my father or grandparents. I have recently had stomach and upper abdomen pain for about 7 days and went to my local healthcare professional for a check-up. I had urine tests shoulded everything alright. My blood work showed everything alright but my GGT, AST, and ALT lvls were high. My ast was about 59 (0-50 normal), but my GGT was about 494, and my AST was about the dame as the GGT. I am fairly young, have never drank alcohol, smoked, and eat well, I did have a liver infection a few years ago but it wasn't that bad and eventually went away without the use of medication. My doctor I saw prescribed me, "Hysocyamine" for the pain which isn't stabbing but is more like a slow throbbing pain. Can you give me some advice on what may be happening and what I should do? I am going to be scheduling myself for a liver examination later in the week. But i would like some more input on what else I should do.

[Graver13]

I had all my vaccinations a while ago, maybe about 4-6 years ago. I also just learned my mother has NAFLD (non-alcoholic fatty liver disease) and my brother did have gul-bladder surgery last march because he had gul stones. As for advil and tylenol I have only taken them maybe once or twise every other day.

Thanks for your guys responses, I'll let my physician know.

[debnevada]

for an acute hep episode of any type, your ALT isn't THAT high. High enough but not dangerously so.

[merryBe]

for some reason we don't see docs in here, on the gastro forum there are a couple.
you should have a complete liver work up including for hep a, b and c,, if any are positive you will need a further tests, assuming you have not been vaccinated for hep a or b, a positive would mean you have one of these. Assuming you test positive for hep c, for which their is no vaccine, they would do the Viral Load and DNA/RNA testing necessary to confirm whether you indeed have that virus, and if so what genotype and other indicators of stage of damage.

there are families who have genetically weak livers. Also fatty livers run in some non-alcoholic families so you may not have a virus, but just this. You definitely want to get seen right away as throbbing pain can be from an infected gall bladder about to explode (not good) or from a blockage in the liver of gall ducts, or from liver inflammation, none of these are good.
extramely rare also, the common bilary duct can get plugged with a "stone" fatty blob issuing from the gall bladder....if it gets stuck at a certain point in the buct it can block not only bile but also pancreatic secretions. If this happens, the pancreas can digest itself.
NOT trying to scare you, just saying, do not just medicate and hope it will pass, get to a liver specialist, or a gasto guy, if the wait it too long for the other to get testing started.
be sure to start with a hepatitis screen as it is the largest blood borne disease, 70 million world wide, and that's only what they know of, there are far more carriers than known cases.

also some meds can elevate enzymes, as can other health issues. Hard to know without all that history if something else is adding to it, but certainly the pain is telling you something.
since there are almost no nerves in the Liver itself, by the time pain comes it means inflammation is causing pressure on surronding tissue with nerve's in them, and that means you deal with this as if your life may depend on it because there is no way of knowing that it does not.

your doctor may want you to have an upper and even lower endoscopy to rule out ulcers, gerd, diverticulitis etc. that's all well and good, even ultrasound may show a blocked ducts, but does not reveal liver damage...........so you need to not buy the, there's nothing wrong with you jive.
I had all those tests, and they were negative, and STILL my liver was at stage 3/4 ....so be persistant, ask for the right tests, if you don't fight for a correct diagnosis don't expect anyone else to. stay in here and read up until you do get answers.

I'd lay off of the advil and tylenol as much as possible until you do figure it out.
ps. you don't have to be old to get hep....it's an equal opportunity destroyer. every age group is vunerable.
i'd also ask to be tested for h. pylori, which can pass amongst family members and account for stomach probs and ulcers very similar to liver issues, although whether this would explain your elevations.
you did say you had cleared a liver infection years ago....these things can reoccur either through relaspse or reexposure. The fact that you supposedly cleared an infection years ago doesn't mean it was gone gone as tests were less accurate  years ago.You could have harbored a few undetectible viral cells. So again, i'd start with the liver, and move out from there.
Hope that helps.

[Graver13]

I'm 23 years old, student, 219 pounds, 6'3'. I do take advil liquid gels or extra strength tylinol for headaches. I rarely have been sick.