thank you looks like a very very interseting site rose
It's probably a good idea for you to do some reading on your own. There are so many good liver sites, especially janis7hepc, where all the basic terms are clearly explained.
Iam new here on this post. I found out I have HEP C about 4 years ago..I did 2 differ type of treatments... I discontiued them for it was very horrible for me to witstand.... so now Iam not on anything .But would like to try supplements... I just do not understand everyone DR language in here about viral load ,FIBROSURE,ALT, AST... MY DOCTOR HAS NEVER EXPLAIN TO ME ANY OF these THINGS SO i DO NOT KNOW WHERE IAM AS FAR AS NUMBERS GO,,ONE THING HE DID TELL ME FROM MY LAST BLOOD TEST IS MY NUMBERS WERE IN THE MILLIONS... Can someone please tell me exactly what I should be finding out from him,,, as far as numbers and names that match the numbers...also I never did find out the numbers from my biospy which was done around 4 years ago they could not find a good piece of liver thats all i know.... please tell me what is very important for me to find out? thanx for all who apply....rose
On my first time around my doctors also told me not to worry about my ALT or AST levels. They said there were too many other factors that can elevate them. As long as they arent outrageously high they pretty much ignored them . The viral load is the biggest indicator for now.
Hey, many know my little personal quest with finding some answers or some sort of explanation about "acceptable" ALT level during tx..
Well, I haven't found any real articles or studies on it, but I have recieved personal replies from numerous Dr's about it..
First Dr said it is absolutely meaningless. Active viral infection would show in VL, and in one of the CBC's in think it was the Lymphocytes.. If they are elevated or rise during TX, this is a precursor for hepatic inflamation occuring..Told me there was WAY to many favorable factor in my situation to be concerned over the just outta range ALT levels.
Second DR told me to focus on my accomplishment, week 12 and 24 undetectable PCR.. He explained that the theory around the medical community right now is that the elevated levels can be the dying off of fibrosis cells and scar tissue in the liver. He has documented several cases in which patients undergoing tx, starting tx with significant fibrosis, never obtained "normal" ALT levels, and still obtained SVR... He also said that this is also what convinces him this theory is accurate, as these same patients saw the greatest reductions in fibrosis post TX SVR..Same DR also told me that my physical condition, being so young and active, plays a part in my ALT's.. AS physical activity and excercise play a part in muscle cell destruction and regeneration which in turn raise ALT's.. He seemed to think that the initial spike in ALT levels during the first 2 weeks was the meds eradicating my LOW VL right off the bat.
Third DR told me not to worry, and that the PCR is what is important. ALT level can be elevated just from the presence of the Meds, let alone sooo many other natural factors around us in daily life. Many patients never obtain "normal" ALT levels until discontinuation of treatment.She also stated what the first Dr said about rise in Lymphocytes.. But not just a slight increase, a spike in levels that stays elevated..She told me that almost 85% of her patients within the similar age group as myself, obtain SVR based off week 12, 24, and 48 undetectable PCR.
One Dr was my current advisor, and works under the guidance of DR Schiff. The other two where from respectable Hepatitis sites in which patients can submit questions. The one site, the director of the research department answered my question as he was greatly intrigued.. This was the second opinion..
Hope any of this info helps.
Very interesting. Thanks much for posting this.
His triple antioxidant therapy? Very good idea. You ever check out the Hep C Choices handbook at www.hepcchallenge.org/ ?