Have you had your thyroid checked since coming off the Interferon? Swelling of the eyes and puffy face are symptoms of thyroid dysfunction. Have your doctor test your tsh levels
Haven't had that problem but I know you do not want to sleep in contacts.. I woke up the other night and realized I didn't take it out and it was stuck to my eye. While trying to get it out it scratched my eye and could not wear for 2 days. I guess they dry out too much, which causew them to stick. thank goodness I only wear one