Aa
child with hepatitis C
HI
I have heard something else.... that the couple who has PCR RNA negative(means one from them had heptitis C some time ago and after cleared the virus he/she u can say went to produce child) when child born, it was not has any kind of hepatitis.but after some months child's PCR was positive BECAUSE his mother or father has hepatitis some years ago............
a doctor who was doing house job at PIMS (Paksitan institue of Medicle Science) told me the story........
can anybody helop me is it it true?
can anybody give me the reason how is it possible?
I have heard something else.... that the couple who has PCR RNA negative(means one from them had heptitis C some time ago and after cleared the virus he/she u can say went to produce child) when child born, it was not has any kind of hepatitis.but after some months child's PCR was positive BECAUSE his mother or father has hepatitis some years ago............
a doctor who was doing house job at PIMS (Paksitan institue of Medicle Science) told me the story........
can anybody helop me is it it true?
can anybody give me the reason how is it possible?
If your antibody test is positive and your PCR is negative, then you can't pass it on active/chronic Hepatitis C to your child. Simple as that. There is nothing to pass on, nothing infectious to infect them with.
Trin provided a more complex answer that's probably closer to the truth than a strictly economic one.
It could make us feel a bit second-class to be rejected for something we no longer have but from a wider perspective, better safe than sorry.
It could make us feel a bit second-class to be rejected for something we no longer have but from a wider perspective, better safe than sorry.
I'm not sure what the whole story is but this is what I heard from an economics point of view.
When screening potential blood donors, a relatively inexpensive and quick HCV antibody test is used.
The HCV RNA PCR test is not only very expensive but requires much more processing time and often has to be sent away. Therefore, it is more efficient to eliminate all potential donors who test positive for antibodies, using quick and inexpensive testing.
Whether this is a plausible explanation, I don't know. It does make sense to me but also makes me feel a bit bad that I'd be excluded from donating if I don't have the virus.
If you're SVR, you don't have any virus in your blood
When screening potential blood donors, a relatively inexpensive and quick HCV antibody test is used.
The HCV RNA PCR test is not only very expensive but requires much more processing time and often has to be sent away. Therefore, it is more efficient to eliminate all potential donors who test positive for antibodies, using quick and inexpensive testing.
Whether this is a plausible explanation, I don't know. It does make sense to me but also makes me feel a bit bad that I'd be excluded from donating if I don't have the virus.
If you're SVR, you don't have any virus in your blood
I'm not exactly sure why we can't donate but I think I have an idea. I've seen it posted her before but can't remember exactly.
I think it has something to do with the fact that they can't because of cost factors do additional testing on every donor who tests positive for hepc antibodies. HCV RNA can show UND at EOT and the person could relapse. If the virus has returned within the time frame of UND to relapse and the person donates blood, it is tainted. Also, there is chance, small but possible the RNA test is false negative. More so than the person actually being hepc positive after SVR, I think they have put universal precautions in place just to ensure no error of transfer through blood products happens. Actually, even with the precautions in place, transfer by blood products still does happen in small percentages.
Trinity
I think it has something to do with the fact that they can't because of cost factors do additional testing on every donor who tests positive for hepc antibodies. HCV RNA can show UND at EOT and the person could relapse. If the virus has returned within the time frame of UND to relapse and the person donates blood, it is tainted. Also, there is chance, small but possible the RNA test is false negative. More so than the person actually being hepc positive after SVR, I think they have put universal precautions in place just to ensure no error of transfer through blood products happens. Actually, even with the precautions in place, transfer by blood products still does happen in small percentages.
Trinity
you are right but in most of the Asia and i have heared that even in EU and USA ( pls correct me if i am wrong in case of Eu & USA), the blood of those persons having HCV antibody test positive (even they have gone through tx and are pcr negative) is not given to healthy persons. My doctor also advised me , not to donate blood to others even after SVR. my qustion is why is this restriction. If one's PCR is negative and remains negtive for 6 months or for years then why is he restricted to donate blood.
The only way the child could have been HCV RNA positive was if the mother had chronic hepatitis, (not the father) while the mother was carrying the child. If the PCR RNA was negative for the mother she can't pass it to her unborn unless the PCR was a false negative which is highly unlikely but I suppose can happen.
Sam,
You can't pass this virus to an unborn if it does not exist in the blood. If the mother has chronic hepatitis, she can pass it to the child (5% chance) and the child may even show positive for the antibodies because of exposure to the virus but further testing will reveal
negative for the virus. They usually test when the child is 1 yr old. I know you should respect what your doctor tells you but he was incorrect to tell you that. Doctors are not always correct, even in this country.
I've had some experiences with my local hepatologist which left me speechless (and that doesn't happen very often). He was unfamiliar with the latest treatment protocols for hepc and I was forced to seek out another hepatologist.
Stay on the forum and you will learn more than your doctor knows about this virus.
Trinity
Sam,
You can't pass this virus to an unborn if it does not exist in the blood. If the mother has chronic hepatitis, she can pass it to the child (5% chance) and the child may even show positive for the antibodies because of exposure to the virus but further testing will reveal
negative for the virus. They usually test when the child is 1 yr old. I know you should respect what your doctor tells you but he was incorrect to tell you that. Doctors are not always correct, even in this country.
I've had some experiences with my local hepatologist which left me speechless (and that doesn't happen very often). He was unfamiliar with the latest treatment protocols for hepc and I was forced to seek out another hepatologist.
Stay on the forum and you will learn more than your doctor knows about this virus.
Trinity
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