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relapse after enbrel ???

Hi everyone
It's been a long time , I have a question that is bothering me since I went to see my rheumy....
I developed psoriasis arthritis during a treatment with pegintron + riba and is getting worst ..
I was SVR for 3 years now , HCV RNA - und , sensitivity 12 IU/ml
Have a real pain from PsA and have to start treatment with ENBREL which is biological drug and it suppose to lower  my immune system .My rheumy told me that there is tinny possibility of relapsing after taking it..
All this time I thought that once you get rid of virus that is it . How comes it can relapse after 3 years ??? Goggling thru the net couldn't find anything than can give any proof for his theory.
So I don't know what to do ..PAIN is killing me and I tried all other "easier" treatments with no
benefits
I would appreciate to see your thoughts
THANKS
Hope you will understand my english :)
2 Responses
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Avatar universal
Also I meant to add you may want to speak  with a Hepatologist ,given they are dealing with HCV treatments and other diseases of the liver in regards to his/her knowledge about the drug Enbrel and its possible problems post HCV treatment.
Best..
Will
Helpful - 0
Avatar universal
Congratulations on being SVR for three years now. SVR is extremely sustainable as documented in  the study data  I copied below
.
I am not familiar with the treatment that has been recommended to you nor the drug Enbrel,.however for the rheumatologist to tell you it may cause relapse ,I would ask him to show you peer -.reviewed data stating that this drug may be causel of HCV in a patient that has been SVR for 3 years before I would put any weight in just his opinion

Again.. congrats and good luck with the condition you are fighting presently
Will

http://www.medscape.com/viewarticle/716305_4

In conclusion, we have observed that in patients with chronic hepatitis C treated with PEG-IFN and ribavirin, the durability of SVR exceeds 99% for up to 7 years of follow-up. Although 'late' virological relapse may occur in less than 1% of the patients, this phenomenon is mainly confined within 1 year after assessment of the SVR. Clinical outcome of patients who obtain SVR is excellent, although patients with cirrhosis are still at risk of hepatocelluar carcinoma despite HCV-RNA negativization and therefore need adequate surveillance.
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