Aa
Does anyone know if the med for geno type 1 is stronger then med for geno type 2
I'm new to all of this . So does anyone know if the med taking for geno type 1 is different and or stronger then the med taking for geno type 2 ? Also is it the pills or the shot that get you sick and in pain or both?
Sorry. I didn't mean to pass on incorrect info. You are right it is 1a and I am 1a not 1b. Been 10 years and it was not one of my better years to say the least.
As far as Procrit my doctor didn't consider that an option for me. As you must know, anything less than 10 can cause you to have a heart attack. I already had heart problems so my Doctor wanted to play it safe with me. I also was on the prescribed dose I wasn't over taking the ribavarin. (I can't believe anyone would willing take more than the prescribed dose.)
I also thought this was a a support group. Considering some of the comments I guess I was wrong.
As far as Procrit my doctor didn't consider that an option for me. As you must know, anything less than 10 can cause you to have a heart attack. I already had heart problems so my Doctor wanted to play it safe with me. I also was on the prescribed dose I wasn't over taking the ribavarin. (I can't believe anyone would willing take more than the prescribed dose.)
I also thought this was a a support group. Considering some of the comments I guess I was wrong.
48 weeks back in 2000; ribavarin almost killed me, literally. I developed hemolytic anemia to I had a choice quit taking the meds or cut the ribavarin down to get my blood count back up. "
Dont ya think this is a bit overly dramatic? I had a severe and drastic rapid hemo reduction yet I'd hardly say that hemolytic anemia was going to kill me - now with Procrit so easily and deftly upped my hemo back to over 10 and I was able to complete 72 weeks of tx. And my hemo crash was at week 2/3 (my fault I doubled my riba of my own free will).
Yes 1a is the harder. As I had 1a and also 1b it's a fact I'm sure of and the reason I convinced myself to do so much riba in the first place.
Dont ya think this is a bit overly dramatic? I had a severe and drastic rapid hemo reduction yet I'd hardly say that hemolytic anemia was going to kill me - now with Procrit so easily and deftly upped my hemo back to over 10 and I was able to complete 72 weeks of tx. And my hemo crash was at week 2/3 (my fault I doubled my riba of my own free will).
Yes 1a is the harder. As I had 1a and also 1b it's a fact I'm sure of and the reason I convinced myself to do so much riba in the first place.
http://www.hivandhepatitis.com/hep_c/news/2010/011210_b.html
“According to a study in the December 2009 Journal of Medical Virology, subtype 1a is associated with a lower response rate than 1b. Another recent study found that greater diversity of HCV quasispecies -- or minor variations within a single individual -- may increase the likelihood of early virological response…”
“In a univariate analysis, individuals with HCV subtype 1b tended to have a higher sustained response rate (39.0%) than those with subtype 1a (30.6%)(P = 0.06, just short of statistical significance).”
“In conclusion, the study authors wrote, "among difficult-to-treat genotypes, the subtype 1a is associated with a lower response to anti-HCV therapy than subtypes 1b, 4a, and 4d."
Bill
“According to a study in the December 2009 Journal of Medical Virology, subtype 1a is associated with a lower response rate than 1b. Another recent study found that greater diversity of HCV quasispecies -- or minor variations within a single individual -- may increase the likelihood of early virological response…”
“In a univariate analysis, individuals with HCV subtype 1b tended to have a higher sustained response rate (39.0%) than those with subtype 1a (30.6%)(P = 0.06, just short of statistical significance).”
“In conclusion, the study authors wrote, "among difficult-to-treat genotypes, the subtype 1a is associated with a lower response to anti-HCV therapy than subtypes 1b, 4a, and 4d."
Bill
The difference is how each genotype responds to the drugs. 1b responds the worst.
If you don't know if you are 1a or 1b your doctor can test you to see which you are. You really don't need to know what you are because the same drugs are used. I was curious so my doc ran the test. Yea, 1b for me.
48 weeks back in 2000; ribavarin almost killed me, literally. I developed hemolytic anemia to I had a choice quit taking the meds or cut the ribavarin down to get my blood count back up. Needless to say I still had a viral load when I was done.
Now on the new interferon, Pegasis. Any one doing that drug? Took my first shot last night and it was a nightmare!!!!! Temp went up to over 103 and I still feel really sick. I am not sure I can do this again. I watched my brother-in-law die of Hep C at the Cleveland clinic. If it weren't for that I don't think I would bother.
If you don't know if you are 1a or 1b your doctor can test you to see which you are. You really don't need to know what you are because the same drugs are used. I was curious so my doc ran the test. Yea, 1b for me.
48 weeks back in 2000; ribavarin almost killed me, literally. I developed hemolytic anemia to I had a choice quit taking the meds or cut the ribavarin down to get my blood count back up. Needless to say I still had a viral load when I was done.
Now on the new interferon, Pegasis. Any one doing that drug? Took my first shot last night and it was a nightmare!!!!! Temp went up to over 103 and I still feel really sick. I am not sure I can do this again. I watched my brother-in-law die of Hep C at the Cleveland clinic. If it weren't for that I don't think I would bother.
Hi Shane,
How are you? I think both meds make you a little sick. The shot gives you the aches and pains (flu like symptoms) The pills make me nauseous and dizzy. At least that's what I think. Try to take your pills with some food, it helps. Are you drinking enough water?
Hang in there, hopefully you will feel better and at least be able to manage better. It's hard, I know but you can do it.
V
How are you? I think both meds make you a little sick. The shot gives you the aches and pains (flu like symptoms) The pills make me nauseous and dizzy. At least that's what I think. Try to take your pills with some food, it helps. Are you drinking enough water?
Hang in there, hopefully you will feel better and at least be able to manage better. It's hard, I know but you can do it.
V
It's the same stuff for all genotypes just different time periods (geno 48 weeks min. geno2 24 weeks minimum) and both medications can have side effects but so too does hepC have symptoms. You can't worry about things like that because end stage liver disease would be worse than the treatment to kill the disease.
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