Aa
going for CT SCAN tomorrow
Hi again,
Diagnosed with HCV 3 months ago
I saw my doctor today and the results are
Alkaline phosphatase 186 H
AST 138 H
ALT 147 H
Platelets 79,000 L
Biliburin, Direct 0.3 H
Viral Load 288,928 <43 UL/ML
My doctor suspects Cirrohosis so he is ordering CT SCAN and Biopsy. He also talk about treatment.
If it happens that I have Cirrohosis . Can I reberse the cirrrosis with treatment. I have no symptoms except for feeling tire.
Moca3
Diagnosed with HCV 3 months ago
I saw my doctor today and the results are
Alkaline phosphatase 186 H
AST 138 H
ALT 147 H
Platelets 79,000 L
Biliburin, Direct 0.3 H
Viral Load 288,928 <43 UL/ML
My doctor suspects Cirrohosis so he is ordering CT SCAN and Biopsy. He also talk about treatment.
If it happens that I have Cirrohosis . Can I reberse the cirrrosis with treatment. I have no symptoms except for feeling tire.
Moca3
Best Answer
Thank you for the information
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Some patients who achieve SVR (treat successfully) do see improvements in their liver histology and that includes some degree of cirrhosis regression.
Cirrhosis Regression During HCV Therapy Associated With Improved Liver-Related Morbidity, Mortality During Long-term Follow-up
Source: 2008 Annual Meeting of the European Association for the Study of the Liver*
Summary of Key Conclusions
Cirrhosis regression occurs in patients chronically infected with HCV following antiviral therapy and impacts clinical outcome
No liver-related events including cancer, transplantation, or death in patients with regression of cirrhosis even if veremia persists
Should consider cirrhosis regression a primary endpoint in patients with cirrhosis.
http://www.clinicaloptions.com/Hepatitis/Conference%20Coverage/Milan%202008/Hepatitis%20C%20Update/Capsules/12.aspx
HCV Clearance Key to Liver Fibrosis Regression
Megan Brooks
Mar 28, 2013
In addition, cirrhosis regression was more frequent in the sustained virologic responders (11.0%) than in the null responders (2.8%; P = .04) and the treatment-naïve patients (1.6%; P < .001). Regression to liver fibrosis stage F0 to F2 or a decrease in liver stiffness greater than 30% was more frequent in the sustained virologic responders than in the treatment-naïve patients (21.7% vs 7.4%; P < .001). Median liver stiffness decreased significantly in the sustained virologic responders (P < .001) and increased in the null responders (P = .01).
http://www.medscape.com/viewarticle/781610
Good luck,
Mike