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Asymptomatic transmission - Oral Versus Genital HSV-1


After the numberous hours of reading, I have done, I find two questions unanswered.
1:) ASHAD states that oral HSV-1 sheds approximately 5% of the days.  Also stated is HSV "looses its punch" when located out of it's preferred state i.e. genital HSV-1.
Therefore, wouldn't it be true transmission of asymptomatic oral HSV-1 is more likely to be passed on unknowlingly then asymptomatic genital HSV-1?

2:) Are there any studies that have researched recurrent genital HSV1 past 3 years?

I had a symptom once of Genital HSV 1 but it was never diagnosed with a culture.  Later, I received blood tests that confirmed HSV1 positive and HSV2 negative.  I have never seen any recurrent lesions in 7 years since the so thought first episode.

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101028 tn?1419603004
Your anxiety about this that is affecting your work and your relationship is the real issue - not your hsv1 status.  You really need to talk to someone professionally about this as soon as you can. Do yourself and your man a favor and call for some counseling on anxiety.


1) based on you personal experience, does ghsv 1 continue after 7 years if there has never been a ob beside the initial one?

I actually have a friend who had her first hsv1 recurrence, 17 years after her 1st one.  The studies that were done were questionaire's I believe ( been awhile since I read the study ) - unfortunately folks infected with hsv1 genitally for 20+ years are probably hard to come by since cultures weren't always typed that long ago. Only time will tell how it'll be for you - if you even have hsv1 genitally.


2) is ghsv like the other hsv types and locations in that it decreases in ob's after time?

It's different for each person.


3) I've read prior threads and I definitely find a difference in what is stated that: 50% never have another ob, 40% have 1-2 ob's the first 1-2 years then none, and only 10% continually have ob's. Is the most up-to-date info stating that only 10% have ob's after 3 years?
For those of us who have this, there is a huge difference with this number and others that were stated.  I'm just looking for averages as I know it depends on individuals

Once again, you can still have recurrences.  It still sheds. Only time will tell.

grace
Helpful - 0
Avatar universal
Hi Grace,

Sorry to bug you again, but I cannot stop thinking about this and it's affecting my work and relationship.  I was wondering if there was ANYWHERE that gives more accurate information on ghsv1 and reoccurance.
The recent ob i thought i had does not appear to be f ghsv1.  My provider did a PCR which was negative and my boyfriend who is hsv 1 and 2 negative is still negative 2 months out.  So it looks like if i have ghsv1, i've only had the initial ob.
Here are my main questions:
1) based on you personal experience, does ghsv 1 continue after 7 years if there has never been a ob beside the initial one?
2) is ghsv like the other hsv types and locations in that it decreases in ob's after time?
3) I've read prior threads and I definitely find a difference in what is stated that: 50% never have another ob, 40% have 1-2 ob's the first 1-2 years then none, and only 10% continually have ob's. Is the most up-to-date info stating that only 10% have ob's after 3 years?
For those of us who have this, there is a huge difference with this number and others that were stated.  I'm just looking for averages as I know it depends on individuals.

This will be my last post, I realize my prior post rambled on..Thanks again.
Helpful - 0
Avatar universal
My provider is great and very very thorough.  She swabbed a lesion I was concerned about.  The culture came back negative for hsv 1/2 and so did the culture of my cervix. All of the other tests she ran - trichamonosis (sp?), etc came back negative.  The only problem I have is that the defined-boardered lesion of most concern to me was just about gone before i was able to get to her only 3 days after it appeared.  Interestingly, it appeared right after i had sex incuding oral sex.  Both myself and my bf noticed a tug of my skin when he pulled out his fingers in the exact same place the well definied lesion appeared.  Tricky part is that there were a few circles that were defined not in a cluster but in a line also not blisters (but lack of blisters wouldn't be abnormal if it was hsv1 right?)  *Is there a high chance that even if the lesion of concern went away before the swab - that the swab would still pick-up hsv1 if it was present due to clinical shedding.
lastly, we ran tests a week after this happened and my by bf is hsv1and 2 negative.  we are doing another test today to make sure his igg/igm's both come back negative again.

Sorry about all the questions - i have anxiety about this can you tell? :)
Helpful - 0
101028 tn?1419603004
Sores inside the mouth are more typically canker sores and not oral herpes.

A visual diagnosis only isn't accurate. Even the best providers who see genital herpes often, still misdiagnose it 1/3 of the time according to one study.  At this point the only way to confirm PP's visual diagnosis 7 years ago is if you would get a lesion that can be promptly cultured and it comes back hsv1+.  Just no other way to do it unfortunately.

When you were seen recently with symptoms, did your provider find a cause for them?

The duke research isn't out of the test tube yet and it will be years before we know if it's effective or not.  

grace

Helpful - 0
Avatar universal
When I had my 1st and only symptoms 7 years ago of ghsv I obviously was scared to death.  I had been in a relationship for 3 years and have always been extremely careful about protection.  Again, no culture was performed by planned parenthood at the time but the assistant said it was hsv.
However, later I had blood work which confirmed (and has since confirmed) that i am hsv1+ and hsv2-.  My bf at the time didn't have visible cold sore's but later told me he sometimes gets a '***** sore' inside his mouth - which I wouldn't have seen.
My question is how do they know that 50% of ghsv1 people never have another ob if the studies haven't exceeded three years?  My dr thinks I'm being a little too concerned but I am extremely careful about my health and must do the same for my partner.  
This is an extremely hard thought for me to cope with as I have been so careful over the years.  What are the odds right?
What sparked this thought process again recently, is that I thought I had symptoms again - to me it looked very like hsv - but my dr performed a swab and it was negative.  However, now I keep thinking about the situation 7 years ago and am stressing out!  I always thought planned parenhood had made a mistake but now i'm not so sure.

Lastly, how confident are you about the new research being performed by Dr. Cullen at Duke on HSV1?  http://www.genomeweb.com/rnai/embl-exiqon-cenix-cellcentric-duke-university-harvard-university
Helpful - 0
101028 tn?1419603004
It's really too hard to study hsv1 genitally in general. since it sheds so little and reoccurs so infrequently, it's too hard to recruit and keep folks in studies on it.  

Even though most adults have hsv1 orally, only 20-40% of them ever get obvious cold sores to know it. You really can't assume that a lack of oral symptoms means that your hsv1 has to be genital.  It's really unfortunate that you didn't have any proper testing done when you had your symptoms :(  

If your partner has hsv1 too, the risk of transmitting the virus either orally or genitally is too low to worry about. Always avoid sex whenever you have any symptoms going on genitally.

grace
Helpful - 0
Avatar universal
Thank you for answering my questions.  Are there any studies done by Dr. Wald or others where they've studied genital HSV 1 outside of 3 years?
If the they symptoms i had genitally 7 years ago was in fact genital hsv 1, and i have not had any more ob's nor had any facial lesions to my recollection, then it's safe to say I have genital hsv 1 right?

If so, what is some useful information I can gell my partner?
Helpful - 0
101028 tn?1419603004
About 50% of folks who contract hsv1 genitally never get another ob. Of those who do , the average is 1 additional ob the first year and then 1 ob every other year. Only a small percentage of folks have ob's more often with hsv1 genitally. It sheds on average about 3% of days compared to hsv1 orally which sheds on average about 18% of days according to the study referenced in the herpes handbook.

Unless you had a lesion culture done of active symptoms that was hsv1+ or at least hsv+, no way to know for sure if you have hsv1 genitally or not.  You know you've tested + for hsv1 somewhere so discuss this with any potential partners, get them tested too and decide together what precautions if any to take together.  Should you get a return of your genital symptoms, be seen within 24-48 hours of their appearance for a lesion culture and typing to try to confirm if your hsv1 is genital.

Wish I had more definite answers for you but in situations like this, it's the best you can do.

grace
Helpful - 0
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