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Can Herpes PCR test go wrong?

Hi,

Two months after a negative HSV PCR test, I got back sores on penis.
I had HSV pcr test at a popular san francisco hospital and the result was negative. The test was done on fluid collected from penis head and urethral opening, but by then the sore were all gone, except fro some redness.

After the test I have never had sex without a condom.

Two months later I again have sores with whitish layer and itching on the penis head. Can this be yeast infection or should I test for herpes again?
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Avatar universal
You should have a blood test. Testing by swab is only accurate a small percentage of the time -- when the sores are active, new and when the sample is handled properly by the doctors and the lab. Very easy for things to go amiss.

If this has been an ongoing issue, a type-specific IgG blood test should give you some answers as to whether this is a herpes problem or not.
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Avatar universal
Thanks much for the reply. I have setup an appt with a doc tomorrow. I will soon update with the test results.

The sores are not pus filled. But there is whitish layer on the penis head which can be washed away with water. After washing away the red sores become more visible.

When I got tested earlier, the white layer and red sores has almost gone, with one red sore on the penis head and redness at urethral opening. The fact that I had pain during urination, the doc suggested a HSV PCR test. The negative result convinced me that it was Yeast/Cadida.

But the recurrence of the symptoms, make me doubt if its yeast or HSV.
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3149845 tn?1506627771
continued... herpes sores are not puss filled and your symptoms appear more of a fungal or yeast infection.
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3149845 tn?1506627771
Hi a PCR is extremely accurate in detecting the virus but the area swabbed must contain the virus. The urethral opening and the head are not likely places for the virus to be but the shaft and pubic mound areas for new infections and anywhere below the waist for old infections. This test is used on areas where a sore is and should be done within 48 hours after a sore develops. I would retest a new sore or have a blood test.
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