HERPES COMMUNITY
Do IgG and IgM test results vary?

Do IgG and IgM test results vary?

I'm back today from getting the result of a series of blood tests done annually on me...
HIV negative, by the way...
There was three weeks since the last possible exposure when the latest tests were taken...

The lab used in both cases was the same...Todays reading is:
HSV 2 IgM  0.9
HSV1 IgG  0.2
HSV2 IgG  0.6

I looked at a test done by this same lab 2 years ago (I don't have a copy of last years) and it's reading was:
HSV 2 IgM < 0.8
HSV 1 IgG  0.9
HSV 2 IgG 0.2

Type 1 went down, Type 2 went up since the test two years ago.  Does that have any merit? Do these tests vary by either going up or down?  I'm concerned that since the IgG on the type 2 went up .04 percent means that it is rising and will continue to rise, but that doesn't explain why the Type 1 IgG would go down. Do you know why this is?

To finally put this to bed, since I've read the above posting where Dr. Handsfield says: "Totally ignore your recent IgM result with an equivocal outcome.  Almost certainly it is meaningless."  and since my situation is similar where both HSV Type 1 and 2 IgG tests have been negative in the past and remain so....Can I just go on with my life and if I remain asymptomatic, forget about testing for this again?  I am a worrier, big time and would like to put this behind me. Thanks for your help, I appreciate it...

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the differences in your results are meaningless. You can test at the same lab one day and then repeat your lab tests the next and you'll get different results.  All of your results are clear negatives at this point. as you already know, disregard any igm testing and don't allow them to continue ordering it on you.

if you are concerned from your last encounter, you need to repeat the igg 4 months after the encounter to know your status from it.

grace
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This site and your answers have been a big help on calming and educating me.  It's amazing how much more I know in just 24 hours!  
A little backhistory...two years ago an emergency room doctor in LA told me that a rash I had on my behind was herpes, no "it may be" or "that's a possible cause" treated me with Zovirax and sent me on my unmerry way.  After weeks of agony, I got the test results listed in my above post. It's amazing to me the ignorance in the medical community with this disease, which really drives home that it is a medical "practice."  Thank you so much for your input and time..keep up the good work, it's appreciated!
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