I was a very active and happy woman until IC- now I am 55 non active--- do not want to do anything. Takes all I have to do anything. Diagnosed 2 years ago---- The pain, infections and all that goes with this has taken my happiness to a lot of extent. Exhausted and tired of hurting. Now depression has set in which had already taking Lexapro, now I'm just done with it all. Never know when the flare ups are going to attack, have gained weight, tomorrow will go to dr. and ask for something for this pain and depression, cannot keep on. Have done the diets and all. Just done. Anyone else?