Aa
A
A
Close
Avatar universal
Can abx cause elevated bilirubin levels?
Hi,

I have developed slight yellowing of eyes about 8 days in on my Ciproflaxin regimen (500 mx 2x/day).  It is still present 10 days later & doc checked my liver enzymes. Bilirubin levels are slightly high but she wants me to continue the pills. and go in for an ultra sound.  Should I be very concerned and what can be causing this?
Cancel
3 Answers
Page 1 of 1
Avatar universal
I'd be very concerned.
An uncommon but serious side effect of ciprofloxacin is cholestatic jaundice and hepatitis.

See below from: http://www.drugs.com/sfx/cipro-side-effects.html

"Hepatic

Hepatic side effects have included cholestatic jaundice and hepatitis in less than 1% of patients. Hepatic necrosis, hepatic failure (including fatal cases), jaundice, and increased ALT, AST, alkaline phosphatase, LDH, serum bilirubin, and serum GGT have also been reported...."

Jaundice is a serious side effect and I wouldn't continue taking ciprofloxacin without consulting with either a hepatologist or a gastroenterologist. When you see a side effect of "hepatic failure" it's a potentially dangerous situation and it's a lot better to be extremely cautious. I wouldn't take another dose without an expert's advice.

Good luck,
Mike
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Thanks for the advice.  I saw my doc and she had me switch to Doxycline, but I am going to see a gastroenterologist this week.    Condition seems to have improved slightly since stopping Cipro, but still present & for some reason I seem to be bloodshot chronically when I wake up, even after a good nights rest.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
I'm happy that you're seeing a specialist.

Doxycycline is not to my knowledge associated with hepatic injury so it's probably a safer choice. I hope it is effective against whatever it is that you're treating.

I am unaware of any connection between bloodshot eyes and liver disorder.

Good luck,
Mike
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Recent Activity
5986700 tn?1380794980
Blank
spider6 commented on Failed.
Dec 02
317787 tn?1473362051
Blank
Dee1956 Meegy 172 days!! Coincidenc... Comment
Dec 01
5986700 tn?1380794980
Blank
10356, and spider6 commented on stilltrying1965's status
Dec 01
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Digestive Answerers
Liver Disorders Community Resources