Positive ANA with Lyme?

[suega]

I have been experiencing extreme fatigue, muscle twitches all over my body, hyper active knee reflexes, and head/neck/back aches.

My doctor did some basic bloodwork that was all within normal limits except for a Positive ANA 1:320 Speckled.  Now he is sending me to a rheumatology specialist as this is indicative of an autoimmune disease.  I have been reading the symptoms of Lupus and I know the fatique and positive ANA fit, but not anything else.  Maybe joint pain?  Really, I just ache all over. I was thinking maybe MS or even Lyme disease, but what I read says that neither are indicated by positive ANA.  I am going crazy trying to figure this all out as I wait to see the specialist.  Can a positive ANA indicate Lyme?  Any thoughts?

[patsy10]

Welcome.  The symptoms you have are symptoms of lyme but lyme mimicks many other conditions/diseases.  From what I have read a positive ANA is not indicative of lyme but I would ask to be tested for lyme anyway if it were me.  

The ANA is a non-specific test.  It does not necessarily mean you have a disease. But it does mean that further testing needs to be done according to the neurologist I saw.  He also said that many people have positive ANA titers and have nothing wrong with them.