---I had intended to say that 'all over itching' can be part of a 'herx' reaction - toxins from dead bacteria circulating in your body. If your symptoms have gotten worse since taking the 'Amoxicillin' then that could be another indicator of 'herxing', - which would mean the antibiotics are working.
I had 'all over' itching/crawling sensation - I was also on Amoxicillin - it happened several times - it might of been coincidence but when I tried really hard to ignore it and resist the urge to scratch or rub my skin, it would disappear alot quicker! It would start suddenly and end suddenly.
Amox. was the only meds. I was taking at that time.
Sorry to hear about this!
Does your MD know you are taking the sleep meds? If he doesn't, then he wouldn't know if the itching is caused by conflicting meds. You could ask your pharmacist, but s/he might just tell you to ask your MD anyway. It's worth finding out to avoid an unwanted drug interaction.
I am guessing (and I'm not medically trained) that he told you to take the Benadryl in case you are having a mild allergic reaction to the amoxicillin, and if that doesn't work, then either Benadryl is not strong enough (so you would go to the ER for stronger meds) or you are not having an allergic reaction, but something else is going on (in which case you might should go to the ER anyway, since the Dr is 2 hours away). Benadryl is a drug to suppress relatively mild allergic reactions, so it sounds like that's the doc's first stop. He may seem cold, but some docs just don't radiate warmth.
Did he run any tests to see if you have Lyme or other diseases carried by the same ticks? If not, is he going to run any tests after you've been on the meds for a while? The tests for Lyme are not very precise, and sometimes the tests are negative even tho you're infected, so the docs will give a short course of antibiotics (altho I don't know that amoxicillin is or is not effective against Lyme) to see if it stirs up your immune system to make antibodies that can then be detected on tests. That MAY be what he's doing, but he should explain his whole approach to you and know about the sleep meds you are taking.
Hope you feel better soon! Let us know how you do.