A. Going from one pill a day to
Have you looked into using a bio-identical HRT, such as Estradiol? Much better for you, all natural. Best to use it in a patch, cream, or gel, but it would probably be a bit more expensive, unless you got generic, you could check and see. I also feel much better on it. I know the generic patches are cheaper. I like the gel the best though.
You could use it indefinitely with no worries, like those possible from synthetics, in my opinion. Do a search on Estradiol and see what you think.
I used to use the Estratest, but it did not control the lack of sleep and hot flashes totally. Plus it has testosterone in it, and I didn't like that fact of using it all the time.
I also started HRT at 41, am now 55, and used one form or other of it since then. Have used several kinds during that time. Unless something changes, I won't be without it.