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why do I keep miscarrying?

I have had two past miscarriages, an ectopic pregnancy and now am currently going through my third miscarriage.  With all of my pregnancies I have miscarried before 8 weeks. My first miscarriage was when I was 8 weeks, the 2nd was when I was 6 weeks and this one is I am only 3 weeks... the ectopic was really early as well. I have been seeing a doctor to help with my fertility issues.... as I do have PCOS and do not ovulate regularly. This last pregnancy I was on clomid to help ovulation and then we did an IUI... which was successful at getting me pregnant... but I just can't seem to keep being pregnant. It is very frustrating.  My first pregnancy was my only successful one.. and I have a wonderful 6 year old... but since then I have not been able to maintain a pregnancy.... Is there a way to find out why I seem to be miscarrying so early all the time?? I really want to have another baby... but I don't know how many times I can go though this again... and I am losing hope that it will ever happen...  


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Avatar universal
Hi.

I am so sorry for all your losses and my heart goes out to you. I want to share a few things with you because I read your post and it seems we have somethings in common. I have had 6 pregnancies. Out of the 6 I only have a son that is 6 years old the same as you. I have had blighted ovumn, natural miscarriages and also chemical miscarriages. I was on clomid also for about 6 months and it did not work for me. I would have to say that I wish I never took the clomid because there is so much risk involved and I just have a colonoscopy in October. Found out that I had pre-cancerous cells and I do blame the clomis for this.

I know you said that you have had alot of miscarriages. Have you ever had your cervix looked at? Maybe you have a short cervix which would mean that you need to have whats called a cerclage. Please read my post I put up about this. It will explian more ....There is another thing that I was thinking about in your case. Have you and your partner been checked for Chromosomal Abnormalities? This usually occurs early in pregnancy. Like myself 8 months ago I had a blighted ovumn so the baby had a problem growing. I had a empty sac for 6 weeks. Please read this about POCS Traditional treatments have been difficult, expensive and have limited success when used alone. Infertility treatments include weight loss diets, ovulation medications (clomiphene,letrozole, Follistim, Gonal-F), ovarian drilling surgery and IVF. Other symptoms have been managed by anti-androgen medication (birth control pills, spironolactone, flutamide or finasteride).

Ovarian drilling can be performed at the time of laparoscopy. A laser fibre or electrosurgical needle is used to puncture the ovary 10-12 times. This treatment results in a dramatic lowering of male hormones within days. Studies have shown that up to 80% will benefit from such treatment. Many who failed to ovulate with letrozole or metformin therapy will respond when rechallenged with these medications after ovarian drilling. Interestingly, women in these studies who are smokers, rarely responded to the drilling procedure. Side effects are rare, but may result in adhesion formation or ovarian failure if the procedure is performed by an inexperienced surgeon.

For women in the reproductive age range, polycystic ovary syndrome is a serious, common cause of infertility, because of the endocrine abnormalities which accompany elevated insulin levels. There is increasing evidence that this endocrine abnormality can be reversed by treatment with widely available standard medications which are leading medicines used in this country for the treatment of adult onset diabetes, metformin (Glucophage 500 or 850 mg three times per day or 1000mg twice daily with meals), pioglitazone (Actos 15-30 mg once a day), rosiglitazone (Avandia 4-8 mg once daily) or a combination of these medications. These medications have been shown to reverse the endocrine abnormalities seen with polycystic ovary syndrome within two or three months. They can result in decreased hair loss, diminished facial and body hair growth, normalization of elevated blood pressure, regulation or menses, weight loss, reduction in cardiovascular risk factors, normal fertility, and a reduced risk of miscarriage. We have seen pregnancies result in less than two months in woman who conceived in their very first ovulatory menstrual cycle. By six months over 90% of women treated with insulin-lowering agents, diet and exercise will resume regular menses.

The medical literature suggests that the endocrinopathy in most patients with polycystic ovary syndrome can be resolved with insulin lowering therapy. This is clinically very important because the therapy reduces hirsutism, obesity, blood pressure, triglyceride levels, elevated blood clotting factors and facilitates reestablishment of the normal pituitary ovarian cycle, thus often allowing resumption of normal ovulatory cycles and pregnancy. We know the polycystic ovary syndrome is associated with increased risk of heart attack and stroke because of the associated heart attack and stroke risk factors, hypertension, obesity, hyperandrogenism, hypertriglyceridemia, and these are to a large degree resolved by therapy with these medications.


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1421938 tn?1318603558
Im sorry for your.. I also have psco.. Im on metformin 2000mg a day it helps with the psco... It also makes me have my period each month... People with psco r higher risk of mc...I have done alot of googles and I have learned that people with psco that get preg should stay on the metformin until they r 12wks... Metoformin helps keep psco under control when u r preg.. lowers the chance of mc... Good luck to u !!
Helpful - 0
1422615 tn?1334064234
Let me start by saying i am so sorry for your loss. I myself have had two mc but farther along then you. How did u know u were pregnant this time? most women even with the early dection test dont know until 4wks. Are u saying u were 3 wks past iui?

I know your dr can run some test.I have started the test process this week. I am feeling your frustrations. I tried for 3 yrs to get pregnant and after a lappy for endo i feel pregnant naturally. I lost that one at 3months. 5 months later i gave in and did iui.  feel pregnant right away. first 2 us went great then the 3rd the babies heart stopped beating. i lost the baby at 11 wks. I want a child so bad but am not sure that i will ever be able to have one. I can tell u the test they are running and the results when i get them back if u think this will help.
Helpful - 0
Avatar universal
Thank-you for your kind words... I too am sorry for your loss.... In responds to your question... I started having pregnancy symptoms 2 to 3 weeks following the IUI... and did a pregnancy test and it pick up... it was a faint positive but it was still positive... for a week anyways. As for tests... I wish my doctor would do more hormonal testing or maybe even some genetic testing... something at least and not just keeping saying 50% of all pregnancies will end in miscarriage.... If you will share with me what testing you are doing that would be very appreciated.... and I hope everything turns out for you... Good luck to you.

Helpful - 0
Avatar universal
I am sorry for your loss... my doctor did put me on metformin but he didn't tell me it would help with the PCOS... he just told me it would help me lose weight. I was on it for a while but I did not like the side effects it gave me.... perhaps if I had known a little more about how it would help me I might have persevered through the side effects. Thank-you for sharing your experience and knowledge with me... I think I will attempt to take my metformin again.
Helpful - 0
1422615 tn?1334064234
I will have to get a list for u. I can tell u that they did a factor 2, factor 5, carry 0 type, cromozone, hcg quiant, tsh, prolactin, ana, lupus anticoagulant, pt/ptt, anticardiolipin ab, I will get a list for u.  One other thing u should know is that u usally do the iui at what is considered 2 wks pregnant, so at 2 wks after iui u are considered 1 month pregnant. they list it from the date of your last cycles first day.( the they u start af)

hope this helps, i have to run.
Helpful - 0
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