37 y.o. male – Since March ‘06, experienced litany of neurological issues. Most sensory (paresthesias & transient sensation reduction), Slight trouble swallowing before & felt a little “tongue tied”. Also have fasciculations all over body (onset around fall ’06 - not present in flexed muscle - only when relaxed). 3x since ’06, had strange sensation upon flexing my neck - does not radiate down spine-felt like small section of the skin vibrated. Recently, noticed difficulty maintaining erection. Right testicle is much lower than the left & is not nearly as responsive as left upon contraction of PC muscle. Developed anisocoria (maybe 1 – 1.5mm) in one eye with mild ptosis. Vision sometimes “shaky” ( wiggles) when looking @ complex patterns (e.g. oriental rugs) for 1yr. In low light, viewing bright lights vs dark backgrounds (think traffic lights at night or Christmas tree lights) I get a quick “reflex” flash. Appears as circle of glare surrounding light source (maybe 3x as large) then rapidly shrinks down to size of the source. Happens after I blink or if focus is away from the light & then moves back to light source. Only happens wearing contacts, not glasses. Have been to 3 neurologists, nationally known MS DR & toxicologist. Have had the normal workup several times (lyme, thyroid, diabetes, B12, etc. - normal). Have had three MRI’s of head & neck (last was July ’08 & post development of anisocoria / ptosis) – all clear. I have had EMG (leg, arm, etc.) with normal findings. All Dr’s ruled out the bad stuff (MS, ALS), have said my neuro exam is perfect. No other explanation for symptoms. Physically, I in great shape (no issues with walking, movement, can bench 1.5x my weight & squat 2x my weight). So, 1) should Ibe concerned about MS, ALS, etc. given clear MRI x 3 & DR’s opinions, 2) Care to hazard guess as to what is causing these things, 3) could this be psychosomatic, 4) What would you do next if you were in my shoes?