Twitching in arches of both feet and ocassional all over

[DET]

March   Alternating left to right pain in groin
April Saw GP--night sweats, tingling sensations

[CCF-Neuro-M.D.-PW]

If you have a normal objective neurological examination by your neurologists without muscle weakness or wasting, the fasciculations are unliklely to be caused by ALS. Other more common causes of fasciculations include benign fasciculation caused by exercise (ie walking!), cold, certain medications or a syndrome associated with cramps, pinched nerves or some rare viral infections (such as West Nile or Polio). Burning sensations are not a sign of ALS as ALS affects the motor not sensory nerves.

Your MRI findings (although I cannot confirm the accuracy of the scan) seem to be not enough to cause your symptoms, although the ridging at C6,7 in certain body positions could cause some sensory symptoms in the hand. Flexion and extension plain xray views if not done already could tell if there is significant movement during dirrent neck positions of the bones. Have your B12, folate levels, thyroid hormone been done and an RPR checked for syphilis, or a monoclonal protein analysis (if you are older), if not these are simple blood tests.  There are no other specific viral tests, although if you have risk factors for HIV (such as unprotected sex, exposure to infected needles etc) you should get a HIV test. There is no suggestion from the information you provide and in the absence of a focal neurological examination a tumor is also unlikely. I cannot tell you for sure as I have not examined you myself

Good luck

[johnflox]

The first thing you should do is to rule out a drug reaction. Many drugs taken up to a few months earlier can bring the symptoms that you describe. There are hundreds of neurotoxic medicines out there, and they are loosely prescribed. Some very common reactions to certain antibiotics are not even known by most doctors. For instance, quinolone antibiotics are extremely agressive on the nervous system for long treatments or high doses, but some people also develop neuropathies that last for years after only a few pills, without being allergic to them.
Check also all the over the counter remedies, and herbals that you were currently taking.