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I developed severe akathisia after taking SeroquelSeroquel Seroquel xr, RisperdalRisperdal Risperdal consta Risperdal m-tab and ProzacProzac Prozac weekly- we are not sure of which one was the offender- docs think most likely it was the risperdalRisperdal Risperdal consta Risperdal m-tab however prozacProzac Prozac weekly was initiated around the same time. I was on seroquelSeroquel Seroquel xr many years without any difficulty. The seroquel and risperdal were given for sleeping problems and the prozac for anxiety. Anyhow, about 4 months after the addition of the Risperdal I started feeling extremly restless and like I was having constant abdominal spasms. I stopped all 3 of the meds and have been off of them 2 months now. I saw a neurologist who specializes in movement disorders and she is not sure if I have akathisia or dyskinisia, based on the strange location of the symptom. She started me on Xanax and I am up to 2 mg a day- with still lots of suffering. When I first started the xanax and got off all of the meds above I started to feel significantly better- it was there but still manageable and then about 2-3 weeks later I started feeling even worse again. The only thing i can think of that may be contributing to feeling worse is the addition of Rozerem for sleep- which I started about 2 weeks after the xanax. I did research and don't find akathisia associated with it but i do see it can increase restlessness and anxiety. Im thinking I should get off of the rozerem and see how i feel, but then I am back to not sleeping. I am getting more depressed and hopeless that this will never go away. Every other med the doctors talk about putting me on for sleep or depression also carries with it the risk of akathisia or dyskinisia. The neurologist mentioned klonipin as an option to try if the xanax was not effective. The psychiatrist mentioned propranalol but i have very mild asthma and my pulmonary doctor was wary about that. Have you ever seen Rozerem exasperate akathisia? And do you have any other suggests on how I can deal with this horrible feeling. I am also taking vit. E, 200 IU day, vit B6 and B12.