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Ovarian Cancer (Expert Forum)
Good response upto 3 cycles of Gem and carbo
Answered by
Annekathryn Goodman, M.D. - Gynecologic Cancers, Complex Gynecologic, Surgeries, Palliative Care, Acupuncture
Massachusetts General Hospital Cancer Center
Boston - MA
Good response upto 3 cycles of Gem and carbo
by indrasis123, Jun 04, 2009 12:47PM
I wrote you few times earlier and got your valuable suggestions and advises. I need you your help again. just to remind you the history of my mom's OVCA.
First detection March 2006. CA 125= 48..Total hysterectomy foloowed by cisplatin + Taxol. CA 125 remained 11-12.
2nd Detection
January 2008 (After 21 months) Isolated recurrence on Omentum. CA 125 =62.5
Treatment: Infracolic Omentectomy done,
4 cycles doxrubicin +Cyclophophomide and 2 cycles of 5FU.
After 8 moths another isolated recurrence in a Single lymph node 3cmx2.17 (Co eliac region). CA 125 =128 and after 3 months 537.
Treatment : Gemzar +Carbo.....
Result: After 3 cycles Lymphnode became NECROTIC and CA 125 =81 from 537 and CT scan showed everything clear.
After 4th cycle CA 125= 230 but no symtoms of disease anywhere.
Doctor Now Starting Etoposide and Endoxan...
Doctors saying the disease is very slow progressing and always ocurrring in an isolated place. Lymphnode is dead now, so safely we can try these drugs.
What is your opinion with the above mentioned facts? Is there really a chance of long term remission?
First detection March 2006. CA 125= 48..Total hysterectomy foloowed by cisplatin + Taxol. CA 125 remained 11-12.
2nd Detection
January 2008 (After 21 months) Isolated recurrence on Omentum. CA 125 =62.5
Treatment: Infracolic Omentectomy done,
4 cycles doxrubicin +Cyclophophomide and 2 cycles of 5FU.
After 8 moths another isolated recurrence in a Single lymph node 3cmx2.17 (Co eliac region). CA 125 =128 and after 3 months 537.
Treatment : Gemzar +Carbo.....
Result: After 3 cycles Lymphnode became NECROTIC and CA 125 =81 from 537 and CT scan showed everything clear.
After 4th cycle CA 125= 230 but no symtoms of disease anywhere.
Doctor Now Starting Etoposide and Endoxan...
Doctors saying the disease is very slow progressing and always ocurrring in an isolated place. Lymphnode is dead now, so safely we can try these drugs.
What is your opinion with the above mentioned facts? Is there really a chance of long term remission?
Doctor's Answer
by Annekathryn Goodman, M.D., Jun 18, 2009 06:56AM
, Jun 18, 2009 06:56AM
Hi there,
thank you for your update.
Your mother is getting such excelent care. The treatment choices are good.
It is fortunate that your mother has isolated disease. As long as she is not having an symptoms, continuing with therapy and following her CA 125 is very reasonable.
Should she become symtpomatic from this lymph node (such as developng back pain), she could consider some spot radiation to that site.
Please keep us posted as to how she is doing.
best wishes
thank you for your update.
Your mother is getting such excelent care. The treatment choices are good.
It is fortunate that your mother has isolated disease. As long as she is not having an symptoms, continuing with therapy and following her CA 125 is very reasonable.
Should she become symtpomatic from this lymph node (such as developng back pain), she could consider some spot radiation to that site.
Please keep us posted as to how she is doing.
best wishes
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Yes She develops back pain some times but it goes away as soon as she takes digestive Antacid...
Does Necrotic lymph node cause pain?
And Does she need radiation for necrotic lymph node?
Regards
Indrasis
yes it can cause pain. But if it is not constant, I would wait and see what happens from the other therapy
best wishes