Aa
rising CA 125
Hi
My CA125 in April this year was 109, repeated 4 weeks later was 253, then repeated 3 weeks later was 448.5. I had the first one done in April as part of general health check, although then I was going to have hysterectomy as planned surgical procedure for known large adenomyoma. Because of rising CA 125, I had an urgent CT abdomen and pelvis. It showed same large uterine mass most likely an adenomyoma ( 8-9 cms in diameter) and two small ovarian cysts ( 2 cms in diameter) on the right side, I was on day 4 of my cycle. these cysts were not present on transvaginal scan 2 months earlier. There was small amount of free fluid in left para-colic gutter, otherwise rest of abd and pelvis were normal. Subsequently, I underwent TAH and BSO, at the same time peritoneal lavage for cytology and omental biopsy . there was one pelvic lymph node and one paraaortic lymph node on the right side, these were removed for histology.
One week after my operation, I got the news of the histology report. no cancer cells were seen in all specimens, lymph nodes were just reactive nodes.
Now I am in my 5th week postop. I had CA 125 repeated a few days ago- it was 4 weeks after operation. The level was 44.
Would you please share your thoughts and expertise of the answer to rapidly rising CA125 preceding my urgent operation?
Thank you very much.
My CA125 in April this year was 109, repeated 4 weeks later was 253, then repeated 3 weeks later was 448.5. I had the first one done in April as part of general health check, although then I was going to have hysterectomy as planned surgical procedure for known large adenomyoma. Because of rising CA 125, I had an urgent CT abdomen and pelvis. It showed same large uterine mass most likely an adenomyoma ( 8-9 cms in diameter) and two small ovarian cysts ( 2 cms in diameter) on the right side, I was on day 4 of my cycle. these cysts were not present on transvaginal scan 2 months earlier. There was small amount of free fluid in left para-colic gutter, otherwise rest of abd and pelvis were normal. Subsequently, I underwent TAH and BSO, at the same time peritoneal lavage for cytology and omental biopsy . there was one pelvic lymph node and one paraaortic lymph node on the right side, these were removed for histology.
One week after my operation, I got the news of the histology report. no cancer cells were seen in all specimens, lymph nodes were just reactive nodes.
Now I am in my 5th week postop. I had CA 125 repeated a few days ago- it was 4 weeks after operation. The level was 44.
Would you please share your thoughts and expertise of the answer to rapidly rising CA125 preceding my urgent operation?
Thank you very much.
A related discussion, worried about ovarian cancer was started.
MEDICAL PROFESSIONAL
Hi there
CA 125 is not a diagnostic tool and can be quite elevated in inflammation, growing fibroids, endometriosis, and irritation of the lining of the abdomen
What a relief that your tests were benign.
if you have a concern that a cancer could have been missed, you could ask that your pathology be sent to one of the major centers for gyn pathology such as Mass General hospital, Johns Hopkins, Mayo clinic and get a second opinion on the pathology
best wishes
CA 125 is not a diagnostic tool and can be quite elevated in inflammation, growing fibroids, endometriosis, and irritation of the lining of the abdomen
What a relief that your tests were benign.
if you have a concern that a cancer could have been missed, you could ask that your pathology be sent to one of the major centers for gyn pathology such as Mass General hospital, Johns Hopkins, Mayo clinic and get a second opinion on the pathology
best wishes
P.S.
It was adenomyosis in the uterus.
My worry now is that could it have been a chance that very small area of early stage cancer in right ovary was missed? As the follow up is totally different when it was or wasn't a cancer.
It was adenomyosis in the uterus.
My worry now is that could it have been a chance that very small area of early stage cancer in right ovary was missed? As the follow up is totally different when it was or wasn't a cancer.
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