An unexpected negative UDT may have several interpretations.
Talk with the lab/MRO because the drug may be present, but below the lab’s cutoff
concentrations.
Ask for “no threshold testing” to see if the drug is present at low concentration.
• If the prescribed drug is not truly present, one or more of the following may be explanatory:
The patient did not take the drug in the last 1 to 3 days.
The patient excretes the drug or its metabolites faster than normal.
UDT was not sensitive enough to detect the drug (applies to immunoassays).
Clerical errors caused a positive UDT to be reported as negative.
o Patient presented an adulterated specimen.
True negative UDTs raise concerns about drug misuse/addiction (binging, overdosing, or
escalating dose leading to running out early), lost drugs (stolen, misplaced), or even diversion
(selling, giving away drug, diversion to friends, family, or the street).
If you look in my journal pages you will find alot of information and articles on false negitives.
http://www.medhelp.org/user_journals/list/356518?personal_page_id=863283