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I am concerned about my HCG levels. I have been trying to have a child for 8 years and got pregnant naturally. Here’s my numbers 13 DPO hcg-48 progestoerone-32, 15 DPO hcg-103 progesterone 32, 17 DPO hcg-183 prog. 27, and finally 20 DPO 392 prog. 22.
I am nervous as my doubling time is getting longer and progesterone is lowering.
That is correct, studies in viable intrauterine pregnancies have reported the following changes in serum hCG:
-The mean doubling time for the hormone ranges from 1.4 to 2.1 days in early pregnancy (hence the repeating ~ every 48hrs until a diagnosis made).
-In 85 percent of viable intrauterine pregnancies the hCG concentration rises by at least 66 percent every 48 hours during the first 40 days of pregnancy; only 15 percent of viable pregnancies have a rate of rise less than this threshold.
-The slowest recorded rise over 48 hours associated with a viable intrauterine pregnancy was 53 percent.
Based upon what you report, your hCG seems to be rising okay. Given this is a spontaneous pregnancy it is unclear if supplemental progesterone will be helpful. In my patients I don't continue to check Progesterone levels in these circumstances as they are not any more helpful than following the hCG.
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