No I have not heard of Prilosec to help sinus infections. Not sure that those type of medication can really reach the sinus cavities. To control my allergies and sinus infections my doctor prescribed me something called sinus dynamics. They have a nebulizer and medication that is inhaled and let me tell you.........wow! it has worked wonders for me and i have not had a infection since. Maybe try googleing and talk to your doctor.
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